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Search results 1 to 100 out of 1446 for Tbr1

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0.046s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
HT Sample          
Organism Name: mouse, laboratory
Curation Status: Not curated (Transgenic sample)
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Kiyama T
Year: 2019
Journal: Cell Rep
Title: Essential Roles of Tbr1 in the Formation and Maintenance of the Orientation-Selective J-RGCs and a Group of OFF-Sustained RGCs in Mouse.
Volume: 27
Issue: 3
Pages: 900-915.e5
GXD Expression  
Probe: MGI:2665251
Assay Type: RNA in situ
Annotation Date: 2003-07-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:2665253
Age: embryonic day 11.5
Image: 1E Tbr1
Specimen Label: 1E Tbr1
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6148973
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6477322
Age: embryonic day 14.5
Image: 6 Tbr1 +/+
Specimen Label: 6 Tbr1 +/+
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:6148973
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6477322
Age: embryonic day 14.5
Image: 6 Tbr1 -/-
Note: Authors report that neuronal differentiation during early corticogenesis appears normal.
Specimen Label: 6 Tbr1 -/-
Detected: true
Specimen Num: 4
Publication
First Author: Liu S
Year: 2021
Journal: Mol Cell
Title: NRF1 association with AUTS2-Polycomb mediates specific gene activation in the brain.
Volume: 81
Issue: 22
Pages: 4663-4676.e8
Publication      
First Author: Matho KS
Year: 2021
Journal: bioRxiv
Title: Genetic dissection of glutamatergic neuron subpopulations and developmental trajectories in the cerebral cortex.
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270324
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3835655
Age: embryonic day 16.5
Image: 4I Tbr1
Note: Expression is in upper and deep layer neurons.
Specimen Label: 4I Tbr1
Detected: true
Specimen Num: 37
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270324
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3835655
Age: embryonic day 16.5
Image: 4J Tbr1
Specimen Label: 4J Tbr1
Detected: true
Specimen Num: 38
Allele
Name: T-box brain transcription factor 1; targeted mutation 1.1, Chai-An Mao
Allele Type: Targeted
Attribute String: Inducible, Null/knockout, Recombinase, Reporter
Allele
Name: T-box brain transcription factor 1; targeted mutation 1, Z Josh Huang
Allele Type: Targeted
Attribute String: Inducible, Recombinase
Genotype
Symbol: Tbr1/Tbr1
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tbr1/Tbr1<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Fazel Darbandi S
Year: 2018
Journal: Neuron
Title: Neonatal Tbr1 Dosage Controls Cortical Layer 6 Connectivity.
Volume: 100
Issue: 4
Pages: 831-845.e7
Strain
Attribute String: mutant stock, targeted mutation
Genotype
Symbol: Atoh7/Atoh7 Tbr1/Tbr1<+>
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Hevner RF
Year: 2001
Journal: Neuron
Title: Tbr1 regulates differentiation of the preplate and layer 6.
Volume: 29
Issue: 2
Pages: 353-66
Publication
First Author: Liu J
Year: 2018
Journal: Nat Neurosci
Title: Tbr1 instructs laminar patterning of retinal ganglion cell dendrites.
Volume: 21
Issue: 5
Pages: 659-670
Genotype
Symbol: Tbr1/Tbr1 Tg(Six3-cre)69Frty/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tbr1/Tbr1<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pou4f1/Pou4f1<+> Tbr1/Tbr1<+>
Background: involves: 129
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tbr1/Tbr1<+>
Background: involves: 129
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Notwell JH
Year: 2016
Journal: Genome Res
Title: TBR1 regulates autism risk genes in the developing neocortex.
Volume: 26
Issue: 8
Pages: 1013-22
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pou4f1/Pou4f1<+> Tbr1/Tbr1<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Fazel Darbandi S
Year: 2020
Journal: Cell Rep
Title: Enhancing WNT Signaling Restores Cortical Neuronal Spine Maturation and Synaptogenesis in Tbr1 Mutants.
Volume: 31
Issue: 2
Pages: 107495
Publication  
First Author: Imamura F
Year: 2013
Journal: Mol Cell Neurosci
Title: Pax6 regulates Tbr1 and Tbr2 expressions in olfactory bulb mitral cells.
Volume: 54
Pages: 58-70
Publication
First Author: McKenna WL
Year: 2011
Journal: J Neurosci
Title: Tbr1 and Fezf2 regulate alternate corticofugal neuronal identities during neocortical development.
Volume: 31
Issue: 2
Pages: 549-64
Publication
First Author: Huang TN
Year: 2014
Journal: Nat Neurosci
Title: Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality.
Volume: 17
Issue: 2
Pages: 240-7
Publication
First Author: Marinaro F
Year: 2017
Journal: EMBO Rep
Title: MicroRNA-independent functions of DGCR8 are essential for neocortical development and TBR1 expression.
Volume: 18
Issue: 4
Pages: 603-618
Publication
First Author: Han W
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: TBR1 directly represses Fezf2 to control the laminar origin and development of the corticospinal tract.
Volume: 108
Issue: 7
Pages: 3041-6
Publication
First Author: Cánovas J
Year: 2015
Journal: J Neurosci
Title: The Specification of Cortical Subcerebral Projection Neurons Depends on the Direct Repression of TBR1 by CTIP1/BCL11a.
Volume: 35
Issue: 19
Pages: 7552-64
GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2018-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6115537
Age: postnatal day 17
Note: Authors report no difference in expression patterns of cortical layer-selective markers.
Specimen Label: S7i Tbr1 (middle)
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2018-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6115537
Age: embryonic day 15.5
Note: Authors report no difference in expression patterns of cortical layer-selective markers.
Specimen Label: S8g Tbr1 HET
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284227
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6358706
Age: postnatal day 2
Note: Authors state that the ordered six-layer lamination is maintained in the mutant.
Specimen Label: 1E PNKP nes-cre Tbr1
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2018-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6115537
Age: postnatal day 17
Note: Authors report no difference in expression patterns of cortical layer-selective markers.
Specimen Label: S7i Tbr1 (left)
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2018-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6115537
Age: postnatal day 17
Note: Authors report no difference in expression patterns of cortical layer-selective markers.
Specimen Label: S7i Tbr1 (right)
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2018-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6115537
Age: embryonic day 15.5
Note: Authors report no difference in expression patterns of cortical layer-selective markers.
Specimen Label: S8g Tbr1 WT
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2018-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6115537
Age: embryonic day 15.5
Note: Authors report no difference in expression patterns of cortical layer-selective markers.
Specimen Label: S8g Tbr1 KO
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284227
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6358706
Age: postnatal day 2
Specimen Label: 1E Control Tbr1
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6459924
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271121
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6459952
Age: embryonic day 13.5
Note: Expression localized in early postmitotic neurons.
Specimen Label: 1b CP Tbr1
Detected: true
Specimen Num: 1
Publication
First Author: Bedogni F
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex.
Volume: 107
Issue: 29
Pages: 13129-34
Publication
First Author: Englund C
Year: 2005
Journal: J Neurosci
Title: Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortex.
Volume: 25
Issue: 1
Pages: 247-51
Publication
First Author: Büttner N
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Af9/Mllt3 interferes with Tbr1 expression through epigenetic modification of histone H3K79 during development of the cerebral cortex.
Volume: 107
Issue: 15
Pages: 7042-7
GXD Expression    
Probe: MGI:6184829
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191423
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Tbr1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6184829
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191423
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Tbr1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6184829
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191423
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Tbr1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6184829
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191423
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Tbr1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6184829
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191423
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Tbr1
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6184829
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191423
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Tbr1
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6184829
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191423
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Tbr1
Detected: true
Specimen Num: 7
Publication  
First Author: Yook C
Year: 2019
Journal: Front Mol Neurosci
Title: A TBR1-K228E Mutation Induces Tbr1 Upregulation, Altered Cortical Distribution of Interneurons, Increased Inhibitory Synaptic Transmission, and Autistic-Like Behavioral Deficits in Mice.
Volume: 12
Pages: 241
Publication  
First Author: Huang TN
Year: 2019
Journal: Mol Autism
Title: Haploinsufficiency of autism causative gene Tbr1 impairs olfactory discrimination and neuronal activation of the olfactory system in mice.
Volume: 10
Pages: 5
HT Experiment
Series Id: GSE49237
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Bulfone A
Year: 1999
Journal: Mech Dev
Title: Expression pattern of the Tbr2 (Eomesodermin) gene during mouse and chick brain development.
Volume: 84
Issue: 1-2
Pages: 133-8
Publication
First Author: Srinivasan K
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: A network of genetic repression and derepression specifies projection fates in the developing neocortex.
Volume: 109
Issue: 47
Pages: 19071-8
Publication  
First Author: Papachristou P
Year: 2014
Journal: Brain Res
Title: Transgenic increase of Wnt7b in neural progenitor cells decreases expression of T-domain transcription factors and impairs neuronal differentiation.
Volume: 1576
Pages: 27-34
Publication
First Author: Ueno M
Year: 2000
Journal: Gene
Title: Genomic organization, sequence and chromosomal localization of the mouse Tbr2 gene and a comparative study with Tbr1.
Volume: 254
Issue: 1-2
Pages: 29-35
Publication
First Author: Kimura N
Year: 1999
Journal: Brain Res Dev Brain Res
Title: A novel mammalian T-box-containing gene, Tbr2, expressed in mouse developing brain.
Volume: 115
Issue: 2
Pages: 183-93
Publication
First Author: Faedo A
Year: 2002
Journal: Mech Dev
Title: Developmental expression of the T-box transcription factor T-bet/Tbx21 during mouse embryogenesis.
Volume: 116
Issue: 1-2
Pages: 157-60
Publication
First Author: Hancock SN
Year: 1999
Journal: Mech Dev
Title: Mapping and expression analysis of the mouse ortholog of Xenopus Eomesodermin.
Volume: 81
Issue: 1-2
Pages: 205-8
Publication
First Author: Hevner RF
Year: 2002
Journal: J Comp Neurol
Title: Cortical and thalamic axon pathfinding defects in Tbr1, Gbx2, and Pax6 mutant mice: evidence that cortical and thalamic axons interact and guide each other.
Volume: 447
Issue: 1
Pages: 8-17
Publication
First Author: Fujimori A
Year: 2014
Journal: Brain Dev
Title: Disruption of Aspm causes microcephaly with abnormal neuronal differentiation.
Volume: 36
Issue: 8
Pages: 661-9
Publication
First Author: Elsen GE
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map.
Volume: 110
Issue: 10
Pages: 4081-6
Publication  
First Author: Wu JPH
Year: 2022
Journal: Front Mol Neurosci
Title: The Transcription Factor Pou3f1 Sheds Light on the Development and Molecular Diversity of Glutamatergic Cerebellar Nuclear Neurons in the Mouse.
Volume: 15
Pages: 921901
Publication
First Author: Pombero A
Year: 2011
Journal: Development
Title: Pallial origin of basal forebrain cholinergic neurons in the nucleus basalis of Meynert and horizontal limb of the diagonal band nucleus.
Volume: 138
Issue: 19
Pages: 4315-26
Publication
First Author: Fink AJ
Year: 2006
Journal: J Neurosci
Title: Development of the deep cerebellar nuclei: transcription factors and cell migration from the rhombic lip.
Volume: 26
Issue: 11
Pages: 3066-76
Publication  
First Author: Hernández-Acosta NC
Year: 2011
Journal: Brain Res
Title: Dynamic expression of the p53 family members p63 and p73 in the mouse and human telencephalon during development and in adulthood.
Volume: 1372
Pages: 29-40
Publication
First Author: Dennis DJ
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Neurog2 and Ascl1 together regulate a postmitotic derepression circuit to govern laminar fate specification in the murine neocortex.
Volume: 114
Issue: 25
Pages: E4934-E4943
Publication  
First Author: Elsen GE
Year: 2018
Journal: Front Neurosci
Title: The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.
Volume: 12
Pages: 571
Publication
First Author: Yeung J
Year: 2016
Journal: J Neurosci
Title: A Novel and Multivalent Role of Pax6 in Cerebellar Development.
Volume: 36
Issue: 35
Pages: 9057-69
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Huang TN
Year: 2019
Journal: Cell Rep
Title: Interhemispheric Connectivity Potentiates the Basolateral Amygdalae and Regulates Social Interaction and Memory.
Volume: 29
Issue: 1
Pages: 34-48.e4
GXD Expression      
Probe: MGI:6377252
Assay Type: RT-PCR
Annotation Date: 2019-11-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3270426
Stage: TS26
Assay Id: MGI:6377279
Age: embryonic day 18.5
Specimen Label: L
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:6377252
Assay Type: RT-PCR
Annotation Date: 2019-11-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3270422
Stage: TS22
Assay Id: MGI:6377279
Age: embryonic day 14.5
Specimen Label: L
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:2156834
Assay Type: RT-PCR
Annotation Date: 2002-01-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1654226
Stage: TS26
Assay Id: MGI:2156862
Age: embryonic day 18.5
Specimen Label: None
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6781759
Assay Type: RT-PCR
Annotation Date: 2021-10-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716822
Stage: TS22
Assay Id: MGI:6781822
Age: embryonic day 14.5
Specimen Label: not shown
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6781759
Assay Type: RT-PCR
Annotation Date: 2021-10-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716823
Stage: TS23
Assay Id: MGI:6781821
Age: embryonic day 15.5
Image: 5
Specimen Label: E15.5
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:6781759
Assay Type: RT-PCR
Annotation Date: 2021-10-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716823
Stage: TS23
Assay Id: MGI:6781821
Age: embryonic day 15.5
Image: 5
Specimen Label: WT E15.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6781759
Assay Type: RT-PCR
Annotation Date: 2021-10-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716827
Stage: TS27
Assay Id: MGI:6781821
Age: postnatal day 0
Image: 5
Specimen Label: WT P0
Detected: true
Specimen Num: 3