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Search results 1 to 100 out of 2680 for Tbr1

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0.049s
Type Details Score
Gene
Type: gene
Organism: human
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Gene
Type: gene
Organism: frog, western clawed
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Gene
Type: gene
Organism: rat
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Gene
Type: gene
Organism: dog, domestic
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Gene
Type: gene
Organism: chimpanzee
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Gene
Type: gene
Organism: cattle
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Gene
Type: gene
Organism: chicken
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Gene
Type: gene
Organism: macaque, rhesus
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HT Sample          
Organism Name: mouse, laboratory
Curation Status: Not curated (Transgenic sample)
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression  
Probe: MGI:2665251
Assay Type: RNA in situ
Annotation Date: 2003-07-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:2665253
Age: embryonic day 11.5
Image: 1E Tbr1
Specimen Label: 1E Tbr1
Detected: true
Specimen Num: 1
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GXD Expression
Probe: MGI:7382911
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3558827
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7382933
Age: postnatal day 1
Image: S3 Tbr1 P1 -/-
Note: No difference in distribution or expression levels.
Specimen Label: S3 Tbr1 P1 -/-
Detected: true
Specimen Num: 2
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GXD Expression
Probe: MGI:7382911
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7382933
Age: postnatal day 56
Image: S3 Tbr1 P56 +/+
Note: Expression in layers 4-6.
Specimen Label: S3 Tbr1 P56 +/+
Detected: true
Specimen Num: 3
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GXD Expression
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2025-01-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7856695
Age: embryonic day 18.5
Image: S2d Control Tbr1
Note: Expression in neurons in layers V/VI.
Specimen Label: S2d Control Tbr1
Detected: true
Specimen Num: 1
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GXD Expression
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2025-01-29
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7856695
Age: embryonic day 18.5
Image: S2d Yy1cKO Tbr1
Note: Number of expressing neurons decreased compared to control.
Specimen Label: S2d Yy1cKO Tbr1
Detected: true
Specimen Num: 2
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GXD Expression  
Probe: MGI:8215580
Assay Type: Immunohistochemistry
Annotation Date: 2025-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3518526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:8215626
Age: embryonic day 18.5
Image: 7G WT Tbr1
Specimen Label: 7G WT Tbr1
Detected: true
Specimen Num: 3
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GXD Expression  
Probe: MGI:6148973
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6477322
Age: embryonic day 14.5
Image: 6 Tbr1 +/+
Specimen Label: 6 Tbr1 +/+
Detected: true
Specimen Num: 3
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GXD Expression
Probe: MGI:6148973
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6477322
Age: embryonic day 14.5
Image: 6 Tbr1 -/-
Note: Authors report that neuronal differentiation during early corticogenesis appears normal.
Specimen Label: 6 Tbr1 -/-
Detected: true
Specimen Num: 4
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7377788
Age: embryonic day 12.5
Image: 1I Tbr1 E12.5 +/+
Specimen Label: 1I Tbr1 E12.5 +/+
Detected: true
Specimen Num: 1
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GXD Expression
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-31
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7377788
Age: embryonic day 12.5
Image: 1I Tbr1 E12.5 -/-
Note: Decreased number of expressing cells compared to wild type.
Specimen Label: 1I Tbr1 E12.5 -/-
Detected: true
Specimen Num: 2
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7377788
Age: embryonic day 14.5
Image: 1I Tbr1 E14.5 +/+
Specimen Label: 1I Tbr1 E14.5 +/+
Detected: true
Specimen Num: 3
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GXD Expression
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-31
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7377788
Age: embryonic day 14.5
Image: 1I Tbr1 E14.5 -/-
Note: Decreased number of expressing cells compared to wild type.
Specimen Label: 1I Tbr1 E14.5 -/-
Detected: true
Specimen Num: 4
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GXD Expression  
Probe: MGI:8175593
Assay Type: RNA in situ
Annotation Date: 2025-04-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:8175613
Age: embryonic day 13.5
Image: S1C Tbr1 E13.5
Note: Authors report expression patterns consistent with temporal dynamic expression levels detected by RNA-seq and verified by qPCR.
Specimen Label: S1C Tbr1 E13.5
Detected: false
Specimen Num: 2
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GXD Expression  
Probe: MGI:8215580
Assay Type: Immunohistochemistry
Annotation Date: 2025-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:8215626
Age: embryonic day 18.5
Image: 5A WT Tbr1
Specimen Label: 5A WT Tbr1
Detected: true
Specimen Num: 1
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GXD Expression
Probe: MGI:8288223
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:8288291
Age: postnatal day 10
Image: S1A Tbr1 WT
Note: Expression in deep layer.
Specimen Label: S1A Tbr1 WT
Detected: true
Specimen Num: 1
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GXD Expression
Probe: MGI:8288223
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:8288291
Age: postnatal day 10
Image: S1A Tbr1 cKO-Emx1
Note: Thickness of deep layer sharply reduced compared to wild type.
Specimen Label: S1A Tbr1 cKO-Emx1
Detected: true
Specimen Num: 2
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 CTR
Specimen Label: S7o TBR1 CTR
Detected: true
Specimen Num: 1
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 CTR
Specimen Label: S7o TBR1 CTR
Detected: true
Specimen Num: 1
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 CTR
Specimen Label: S7o TBR1 CTR
Detected: true
Specimen Num: 1
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 CTR
Specimen Label: S7o TBR1 CTR
Detected: true
Specimen Num: 1
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 CTR
Specimen Label: S7o TBR1 CTR
Detected: true
Specimen Num: 1
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 CTR
Specimen Label: S7o TBR1 CTR
Detected: true
Specimen Num: 1
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 CTR
Specimen Label: S7o TBR1 CTR
Detected: true
Specimen Num: 1
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 CTR
Specimen Label: S7o TBR1 CTR
Detected: true
Specimen Num: 1
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 CTR
Specimen Label: S7o TBR1 CTR
Detected: true
Specimen Num: 1
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 CTR
Specimen Label: S7o TBR1 CTR
Detected: true
Specimen Num: 1
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 CTR
Specimen Label: S7o TBR1 CTR
Detected: true
Specimen Num: 1
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 CTR
Specimen Label: S7o TBR1 CTR
Detected: true
Specimen Num: 1
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 CTR
Specimen Label: S7o TBR1 CTR
Detected: true
Specimen Num: 1
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 CTR
Specimen Label: S7o TBR1 CTR
Detected: true
Specimen Num: 1
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 cKO
Specimen Label: S7o TBR1 cKO
Detected: true
Specimen Num: 2
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 cKO
Specimen Label: S7o TBR1 cKO
Detected: true
Specimen Num: 2
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 cKO
Specimen Label: S7o TBR1 cKO
Detected: true
Specimen Num: 2
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 cKO
Specimen Label: S7o TBR1 cKO
Detected: true
Specimen Num: 2
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 cKO
Specimen Label: S7o TBR1 cKO
Detected: true
Specimen Num: 2
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 cKO
Specimen Label: S7o TBR1 cKO
Detected: true
Specimen Num: 2
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 cKO
Specimen Label: S7o TBR1 cKO
Detected: true
Specimen Num: 2
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 cKO
Specimen Label: S7o TBR1 cKO
Detected: true
Specimen Num: 2
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 cKO
Specimen Label: S7o TBR1 cKO
Detected: true
Specimen Num: 2
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 cKO
Specimen Label: S7o TBR1 cKO
Detected: true
Specimen Num: 2
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 cKO
Specimen Label: S7o TBR1 cKO
Detected: true
Specimen Num: 2
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 cKO
Specimen Label: S7o TBR1 cKO
Detected: true
Specimen Num: 2
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•
GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 cKO
Specimen Label: S7o TBR1 cKO
Detected: true
Specimen Num: 2
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GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2026-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:8289043
Age: embryonic day 12.5
Image: S7o TBR1 cKO
Specimen Label: S7o TBR1 cKO
Detected: true
Specimen Num: 2
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GXD Expression  
Probe: MGI:8215580
Assay Type: Immunohistochemistry
Annotation Date: 2025-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:8215626
Age: embryonic day 18.5
Image: 7F WT Tbr1
Specimen Label: 7F WT Tbr1
Detected: true
Specimen Num: 2
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GXD Expression
Probe: MGI:8175593
Assay Type: RNA in situ
Annotation Date: 2025-04-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:8175613
Age: embryonic day 11.5
Image: S1C Tbr1 E11.5
Note: Authors report expression patterns consistent with temporal dynamic expression levels detected by RNA-seq and verified by qPCR.
Specimen Label: S1C Tbr1 E11.5
Detected: true
Specimen Num: 1
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GXD Expression
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2025-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:8188168
Age: embryonic day 14.5
Image: 2D TBR1 KO
Note: Authors report a decreased number of expressing cells compared to control.
Specimen Label: 2D TBR1 KO
Detected: true
Specimen Num: 2
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GXD Expression
Probe: MGI:7382911
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3558827
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7382933
Age: postnatal day 1
Image: S3 Tbr1 P1 +/+
Note: Expression in layers 4-6.
Specimen Label: S3 Tbr1 P1 +/+
Detected: true
Specimen Num: 1
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GXD Expression
Probe: MGI:7382911
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7382933
Age: postnatal day 56
Image: S3 Tbr1 P56 -/-
Note: No difference in distribution or expression levels.
Specimen Label: S3 Tbr1 P56 -/-
Detected: true
Specimen Num: 4
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GXD Expression  
Probe: MGI:8175593
Assay Type: RNA in situ
Annotation Date: 2025-04-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:8175613
Age: embryonic day 15.5
Image: S1C Tbr1 E15.5
Note: Authors report expression patterns consistent with temporal dynamic expression levels detected by RNA-seq and verified by qPCR.
Specimen Label: S1C Tbr1 E15.5
Detected: false
Specimen Num: 3
•
•
•
•
•
GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2025-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:8188168
Age: embryonic day 14.5
Image: 2D TBR1 CTL
Specimen Label: 2D TBR1 CTL
Detected: true
Specimen Num: 1
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Publication
First Author: Fazel Darbandi S
Year: 2018
Journal: Neuron
Title: Neonatal Tbr1 Dosage Controls Cortical Layer 6 Connectivity.
Volume: 100
Issue: 4
Pages: 831-845.e7
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Publication
First Author: Hevner RF
Year: 2001
Journal: Neuron
Title: Tbr1 regulates differentiation of the preplate and layer 6.
Volume: 29
Issue: 2
Pages: 353-66
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Publication
First Author: Liu J
Year: 2018
Journal: Nat Neurosci
Title: Tbr1 instructs laminar patterning of retinal ganglion cell dendrites.
Volume: 21
Issue: 5
Pages: 659-670
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•
•
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GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270324
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3835655
Age: embryonic day 16.5
Image: 4I Tbr1
Note: Expression is in upper and deep layer neurons.
Specimen Label: 4I Tbr1
Detected: true
Specimen Num: 37
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•
•
•
•
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270324
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3835655
Age: embryonic day 16.5
Image: 4J Tbr1
Specimen Label: 4J Tbr1
Detected: true
Specimen Num: 38
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Publication
First Author: Co M
Year: 2022
Journal: J Neurosci
Title: Shared and Distinct Functional Effects of Patient-Specific Tbr1 Mutations on Cortical Development.
Volume: 42
Issue: 37
Pages: 7166-7181
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Publication
First Author: Notwell JH
Year: 2016
Journal: Genome Res
Title: TBR1 regulates autism risk genes in the developing neocortex.
Volume: 26
Issue: 8
Pages: 1013-22
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Publication
First Author: Co M
Year: 2025
Journal: Autism Res
Title: Detailed phenotyping of Tbr1-2A-CreER knock-in mice demonstrates significant impacts on TBR1 protein levels and axon development.
Volume: 18
Issue: 5
Pages: 922-932
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Publication
First Author: Fazel Darbandi S
Year: 2020
Journal: Cell Rep
Title: Enhancing WNT Signaling Restores Cortical Neuronal Spine Maturation and Synaptogenesis in Tbr1 Mutants.
Volume: 31
Issue: 2
Pages: 107495
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Publication  
First Author: Imamura F
Year: 2013
Journal: Mol Cell Neurosci
Title: Pax6 regulates Tbr1 and Tbr2 expressions in olfactory bulb mitral cells.
Volume: 54
Pages: 58-70
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Publication
First Author: Huang TN
Year: 2014
Journal: Nat Neurosci
Title: Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality.
Volume: 17
Issue: 2
Pages: 240-7
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Publication
First Author: McKenna WL
Year: 2011
Journal: J Neurosci
Title: Tbr1 and Fezf2 regulate alternate corticofugal neuronal identities during neocortical development.
Volume: 31
Issue: 2
Pages: 549-64
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Publication
First Author: Fazel Darbandi S
Year: 2022
Journal: J Neurodev Disord
Title: LiCl treatment leads to long-term restoration of spine maturation and synaptogenesis in adult Tbr1 mutants.
Volume: 14
Issue: 1
Pages: 11
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Publication
First Author: Marinaro F
Year: 2017
Journal: EMBO Rep
Title: MicroRNA-independent functions of DGCR8 are essential for neocortical development and TBR1 expression.
Volume: 18
Issue: 4
Pages: 603-618
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Publication  
First Author: Yook C
Year: 2019
Journal: Front Mol Neurosci
Title: A TBR1-K228E Mutation Induces Tbr1 Upregulation, Altered Cortical Distribution of Interneurons, Increased Inhibitory Synaptic Transmission, and Autistic-Like Behavioral Deficits in Mice.
Volume: 12
Pages: 241
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Publication
First Author: Han W
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: TBR1 directly represses Fezf2 to control the laminar origin and development of the corticospinal tract.
Volume: 108
Issue: 7
Pages: 3041-6
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Publication
First Author: C?novas J
Year: 2015
Journal: J Neurosci
Title: The Specification of Cortical Subcerebral Projection Neurons Depends on the Direct Repression of TBR1 by CTIP1/BCL11a.
Volume: 35
Issue: 19
Pages: 7552-64
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Publication
First Author: Easton CR
Year: 2016
Journal: Dev Neurobiol
Title: Distinct calcium signals in developing cortical interneurons persist despite disorganization of cortex by Tbr1 KO.
Volume: 76
Issue: 7
Pages: 705-20
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Publication
First Author: Bedogni F
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex.
Volume: 107
Issue: 29
Pages: 13129-34
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Publication  
First Author: Huang TN
Year: 2019
Journal: Mol Autism
Title: Haploinsufficiency of autism causative gene Tbr1 impairs olfactory discrimination and neuronal activation of the olfactory system in mice.
Volume: 10
Pages: 5
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•
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Publication
First Author: Englund C
Year: 2005
Journal: J Neurosci
Title: Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortex.
Volume: 25
Issue: 1
Pages: 247-51
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Publication
First Author: Kiyama T
Year: 2019
Journal: Cell Rep
Title: Essential Roles of Tbr1 in the Formation and Maintenance of the Orientation-Selective J-RGCs and a Group of OFF-Sustained RGCs in Mouse.
Volume: 27
Issue: 3
Pages: 900-915.e5
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Publication
First Author: B?ttner N
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Af9/Mllt3 interferes with Tbr1 expression through epigenetic modification of histone H3K79 during development of the cerebral cortex.
Volume: 107
Issue: 15
Pages: 7042-7
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•
•
•
•
GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2018-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6115537
Age: postnatal day 17
Note: Authors report no difference in expression patterns of cortical layer-selective markers.
Specimen Label: S7i Tbr1 (middle)
Detected: true
Specimen Num: 2
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•
•
•
GXD Expression    
Probe: MGI:8434029
Assay Type: Immunohistochemistry
Annotation Date: 2026-09-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:8434039
Age: postnatal adult
Specimen Label: S4E TBR1 HET
Detected: true
Specimen Num: 10
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•
•
•
•
GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2018-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6115537
Age: embryonic day 15.5
Note: Authors report no difference in expression patterns of cortical layer-selective markers.
Specimen Label: S8g Tbr1 HET
Detected: true
Specimen Num: 5
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•
•
•
•
GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284227
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6358706
Age: postnatal day 2
Note: Authors state that the ordered six-layer lamination is maintained in the mutant.
Specimen Label: 1E PNKP nes-cre Tbr1
Detected: true
Specimen Num: 2
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•
•
•
•
GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2018-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6115537
Age: postnatal day 17
Note: Authors report no difference in expression patterns of cortical layer-selective markers.
Specimen Label: S7i Tbr1 (left)
Detected: true
Specimen Num: 1
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•
•
•
•
GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2018-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3558828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6115537
Age: postnatal day 17
Note: Authors report no difference in expression patterns of cortical layer-selective markers.
Specimen Label: S7i Tbr1 (right)
Detected: true
Specimen Num: 3
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•
•
•
•
GXD Expression    
Probe: MGI:8434029
Assay Type: Immunohistochemistry
Annotation Date: 2026-09-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:8434039
Age: postnatal adult
Specimen Label: S4E TBR1 WT
Detected: true
Specimen Num: 9
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•
•
•
•
GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2018-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6115537
Age: embryonic day 15.5
Note: Authors report no difference in expression patterns of cortical layer-selective markers.
Specimen Label: S8g Tbr1 WT
Detected: true
Specimen Num: 4
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•
•
•
•
GXD Expression  
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2018-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6115537
Age: embryonic day 15.5
Note: Authors report no difference in expression patterns of cortical layer-selective markers.
Specimen Label: S8g Tbr1 KO
Detected: true
Specimen Num: 6
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•
•
•
•
GXD Expression    
Probe: MGI:5762883
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284227
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6358706
Age: postnatal day 2
Specimen Label: 1E Control Tbr1
Detected: true
Specimen Num: 1
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•
•
•
•
GXD Expression    
Probe: MGI:8434029
Assay Type: Immunohistochemistry
Annotation Date: 2026-09-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:8434039
Age: postnatal adult
Specimen Label: S4C TBR1 WT
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression    
Probe: MGI:8434029
Assay Type: Immunohistochemistry
Annotation Date: 2026-09-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:8434039
Age: postnatal adult
Specimen Label: S4C TBR1 HET
Detected: true
Specimen Num: 8
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•
•
•
•
GXD Expression  
Probe: MGI:6459924
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271121
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6459952
Age: embryonic day 13.5
Note: Expression localized in early postmitotic neurons.
Specimen Label: 1b CP Tbr1
Detected: true
Specimen Num: 1
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•
•
•
•
GXD Expression  
Probe: MGI:8434029
Assay Type: Immunohistochemistry
Annotation Date: 2026-09-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:8434039
Age: embryonic day 18.5
Note: Expression in layer 5 neurons.
Specimen Label: 4E TBR1 WT
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression  
Probe: MGI:8434029
Assay Type: Immunohistochemistry
Annotation Date: 2026-09-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:8434039
Age: embryonic day 18.5
Note: Expression in layer 5 neurons.
Specimen Label: 4E TBR1 WT
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression  
Probe: MGI:8434029
Assay Type: Immunohistochemistry
Annotation Date: 2026-09-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:8434039
Age: embryonic day 18.5
Note: Expression in layer 5 neurons.
Specimen Label: 4E TBR1 WT
Detected: true
Specimen Num: 1
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•
•