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Search results 1 to 100 out of 736 for Tet2

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Hits by Strain

Type Details Score
Gene
54790 | TET2
Type: gene
Organism: human
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Gene
100380145 | tet2
Type: gene
Organism: frog, western clawed
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Gene
310859 | Tet2
Type: gene
Organism: rat
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Gene
471263 | TET2
Type: gene
Organism: chimpanzee
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Gene
478499 | TET2
Type: gene
Organism: dog, domestic
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Gene
538481 | TET2
Type: gene
Organism: cattle
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Gene
422540 | TET2
Type: gene
Organism: chicken
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Gene
694137 | TET2
Type: gene
Organism: macaque, rhesus
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Gene
101887161 | tet2
Type: gene
Organism: zebrafish
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Protein Coding Gene
MGI:2443298 | Tet2
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
104384744 | TET2-AS1
Type: gene
Organism: human
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Publication
23353889 | J:194478
First Author: Deplus R
Year: 2013
Journal: EMBO J
Title: TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS.
Volume: 32
Issue: 5
Pages: 645-55
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Publication
21723200 | J:174053
First Author: Moran-Crusio K
Year: 2011
Journal: Cancer Cell
Title: Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation.
Volume: 20
Issue: 1
Pages: 11-24
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Publication
21803851 | J:178415
First Author: Li Z
Year: 2011
Journal: Blood
Title: Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies.
Volume: 118
Issue: 17
Pages: 4509-18
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Publication
38482502 | J:351635
First Author: Li Q
Year: 2024
Journal: iScience
Title: TET2 regulation of alcoholic fatty liver via Srebp1 mRNA in paraspeckles.
Volume: 27
Issue: 3
Pages: 109278
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Publication
23352810 | J:194056
First Author: Dawlaty MM
Year: 2013
Journal: Dev Cell
Title: Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development.
Volume: 24
Issue: 3
Pages: 310-23
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Publication
23222540 | J:306583
First Author: Chen Q
Year: 2013
Journal: Nature
Title: TET2 promotes histone O-GlcNAcylation during gene transcription.
Volume: 493
Issue: 7433
Pages: 561-4
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Publication
31618637 | J:284703
First Author: Carrillo-Jimenez A
Year: 2019
Journal: Cell Rep
Title: TET2 Regulates the Neuroinflammatory Response in Microglia.
Volume: 29
Issue: 3
Pages: 697-713.e8
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Publication
28826859 | J:329670
 
First Author: Cull AH
Year: 2017
Journal: Exp Hematol
Title: Tet2 restrains inflammatory gene expression in macrophages.
Volume: 55
Pages: 56-70.e13
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Publication
36351399 | J:331491
First Author: Pratt KJB
Year: 2022
Journal: Cell Rep
Title: Loss of neuronal Tet2 enhances hippocampal-dependent cognitive function.
Volume: 41
Issue: 6
Pages: 111612
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Publication
41329076 | J:387553
First Author: Wang D
Year: 2025
Journal: FASEB J
Title: Tet2 Protects Against Isoniazid-Induced Hepatotoxicity via Regulating Autophagy.
Volume: 39
Issue: 23
Pages: e71300
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Publication
33589517 | J:305554
First Author: Lee M
Year: 2021
Journal: Cancer Res
Title: Tet2 Inactivation Enhances the Antitumor Activity of Tumor-Infiltrating Lymphocytes.
Volume: 81
Issue: 8
Pages: 1965-1976
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Publication
29150566 | J:253340
First Author: Carty SA
Year: 2018
Journal: J Immunol
Title: The Loss of TET2 Promotes CD8(+) T Cell Memory Differentiation.
Volume: 200
Issue: 1
Pages: 82-91
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Publication
28440315 | J:250581
 
First Author: Pan F
Year: 2017
Journal: Nat Commun
Title: Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cells.
Volume: 8
Pages: 15102
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Publication
38773071 | J:365605
First Author: Schiroli G
Year: 2024
Journal: Nat Commun
Title: Cell of origin epigenetic priming determines susceptibility to Tet2 mutation.
Volume: 15
Issue: 1
Pages: 4325
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Publication
26378518 | J:314578
First Author: Mi Y
Year: 2015
Journal: Int J Mol Sci
Title: A Novel Function of TET2 in CNS: Sustaining Neuronal Survival.
Volume: 16
Issue: 9
Pages: 21846-57
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Publication
29364877 | J:274290
First Author: Shen Q
Year: 2018
Journal: Nature
Title: Tet2 promotes pathogen infection-induced myelopoiesis through mRNA oxidation.
Volume: 554
Issue: 7690
Pages: 123-127
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Publication
22469782 | J:185873
First Author: Shide K
Year: 2012
Journal: Leukemia
Title: TET2 is essential for survival and hematopoietic stem cell homeostasis.
Volume: 26
Issue: 10
Pages: 2216-23
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Publication
32934200 | J:297015
First Author: Kim MR
Year: 2020
Journal: Nat Commun
Title: TET2 directs mammary luminal cell differentiation and endocrine response.
Volume: 11
Issue: 1
Pages: 4642
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Publication
34226503 | J:331636
First Author: Bao Y
Year: 2021
Journal: Cell Death Discov
Title: DNA demethylase Tet2 suppresses cisplatin-induced acute kidney injury.
Volume: 7
Issue: 1
Pages: 167
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Publication
41474968 | J:377490
 
First Author: Feng J
Year: 2026
Journal: J Exp Med
Title: Tet2 deficiency-induced expansion of monocyte-derived macrophages promotes liver fibrosis.
Volume: 223
Issue: 2
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Publication
28823558 | J:252191
First Author: Cimmino L
Year: 2017
Journal: Cell
Title: Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression.
Volume: 170
Issue: 6
Pages: 1079-1095.e20
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Publication
42015258 | J:387166
 
First Author: Hao JP
Year: 2026
Journal: J Neuroinflammation
Title: Tet2 deficiency orchestrates Alzheimer's pathogenesis through oxidative mtDNA-driven cGAS-STING activation.
Volume: 23
Issue: 1
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Publication
28167288 | J:274486
 
First Author: Inokura K
Year: 2017
Journal: Exp Hematol
Title: Impact of TET2 deficiency on iron metabolism in erythroblasts.
Volume: 49
Pages: 56-67.e5
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Publication
40189544 | J:364573
First Author: Quansah E
Year: 2025
Journal: Acta Neuropathol Commun
Title: Tet2 loss and enhanced ciliogenesis suppress ?-synuclein pathology.
Volume: 13
Issue: 1
Pages: 71
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Publication
21057493 | J:168342
First Author: Ko M
Year: 2010
Journal: Nature
Title: Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2.
Volume: 468
Issue: 7325
Pages: 839-43
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Publication
23395962 | J:195146
First Author: Costa Y
Year: 2013
Journal: Nature
Title: NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.
Volume: 495
Issue: 7441
Pages: 370-4
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Publication
37402169 | J:341061
First Author: Xu X
Year: 2023
Journal: Cell Rep
Title: Tet2 acts in the lateral habenula to regulate social preference in mice.
Volume: 42
Issue: 7
Pages: 112695
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Publication
34417463 | J:330916
First Author: Rui J
Year: 2021
Journal: Nat Commun
Title: Tet2 Controls the Responses of ? cells to Inflammation in Autoimmune Diabetes.
Volume: 12
Issue: 1
Pages: 5074
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Publication
32929842 | J:301081
First Author: Li S
Year: 2020
Journal: EMBO Rep
Title: TET2 promotes anti-tumor immunity by governing G-MDSCs and CD8(+) T-cell numbers.
Volume: 21
Issue: 10
Pages: e49425
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Publication
32895473 | J:313354
First Author: Guan Y
Year: 2020
Journal: Commun Biol
Title: Context dependent effects of ascorbic acid treatment in TET2 mutant myeloid neoplasia.
Volume: 3
Issue: 1
Pages: 493
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Publication
28104796 | J:239514
First Author: Fuster JJ
Year: 2017
Journal: Science
Title: Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice.
Volume: 355
Issue: 6327
Pages: 842-847
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Publication
27160912 | J:235460
First Author: Montagner S
Year: 2016
Journal: Cell Rep
Title: TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities.
Volume: 15
Issue: 7
Pages: 1566-1579
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Publication
40037360 | J:366527
First Author: Cheng ZL
Year: 2025
Journal: Cell Metab
Title: Pathogen-derived glyoxylate inhibits Tet2 DNA dioxygenase to facilitate bacterial persister formation.
Volume: 37
Issue: 5
Pages: 1137-1151.e5
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Publication
37456851 | J:388951
First Author: Flores JC
Year: 2023
Journal: iScience
Title: Tet2 regulates Sin3a recruitment at active enhancers in embryonic stem cells.
Volume: 26
Issue: 7
Pages: 107170
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Publication
37414790 | J:365279
First Author: Ansari I
Year: 2023
Journal: Nat Commun
Title: TET2 and TET3 loss disrupts small intestine differentiation and homeostasis.
Volume: 14
Issue: 1
Pages: 4005
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Publication
26598602 | J:235991
First Author: Wiehle L
Year: 2016
Journal: Mol Cell Biol
Title: Tet1 and Tet2 Protect DNA Methylation Canyons against Hypermethylation.
Volume: 36
Issue: 3
Pages: 452-61
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Publication
25224413 | J:218683
First Author: Bejar R
Year: 2014
Journal: Blood
Title: TET2 mutations predict response to hypomethylating agents in myelodysplastic syndrome patients.
Volume: 124
Issue: 17
Pages: 2705-12
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Publication
38881534 | J:373299
First Author: Ma X
Year: 2024
Journal: Adv Sci (Weinh)
Title: Targeting Nr2e3 to Modulate Tet2 Expression: Therapeutic Potential for Depression Treatment.
Volume: 11
Issue: 31
Pages: e2400726
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Publication
41782826 | J:381196
First Author: Rui J
Year: 2026
Journal: iScience
Title: Tet2 modulates ER stress responses related to ?-cell death and autoimmunity in diabetes.
Volume: 29
Issue: 3
Pages: 114818
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Publication
37225048 | J:337826
 
First Author: Flores JC
Year: 2023
Journal: Exp Hematol
Title: Comparative analysis of Tet2 catalytic-deficient and knockout bone marrow over time.
Volume: 124
Pages: 45-55.e2
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Publication
23563267 | J:198694
First Author: Ko M
Year: 2013
Journal: Nature
Title: Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX.
Volume: 497
Issue: 7447
Pages: 122-6
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Publication
35658976 | J:347566
First Author: Pandey SP
Year: 2022
Journal: Cell Host Microbe
Title: Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis.
Volume: 30
Issue: 7
Pages: 1003-1019.e10
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Publication
31043609 | J:275527
First Author: Yue X
Year: 2019
Journal: Nat Commun
Title: Loss of TET2 and TET3 in regulatory T cells unleashes effector function.
Volume: 10
Issue: 1
Pages: 2011
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Publication
36030305 | J:329191
First Author: Garcia-Ruiz C
Year: 2022
Journal: Leukemia
Title: Concurrent Zrsr2 mutation and Tet2 loss promote myelodysplastic neoplasm in mice.
Volume: 36
Issue: 10
Pages: 2509-2518
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Publication
27428748 | J:274091
First Author: Zhang X
Year: 2016
Journal: Nat Genet
Title: DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells.
Volume: 48
Issue: 9
Pages: 1014-23
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Publication
34695415 | J:366621
First Author: Boudra R
Year: 2022
Journal: J Invest Dermatol
Title: Regulation of 5-Hydroxymethylcytosine by TET2 Contributes to Squamous Cell Carcinoma Tumorigenesis.
Volume: 142
Issue: 5
Pages: 1270-1279.e2
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Publication
38924753 | J:361325
First Author: Quin C
Year: 2024
Journal: Blood Adv
Title: Chronic TNF in the aging microenvironment exacerbates Tet2 loss-of-function myeloid expansion.
Volume: 8
Issue: 15
Pages: 4169-4180
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Publication
33216286 | J:331061
First Author: Wang H
Year: 2021
Journal: Protein Cell
Title: Roles of Tet2 in meiosis, fertility and reproductive aging.
Volume: 12
Issue: 7
Pages: 578-585
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Publication
29466726 | J:271544
First Author: Gontier G
Year: 2018
Journal: Cell Rep
Title: Tet2 Rescues Age-Related Regenerative Decline and Enhances Cognitive Function in the Adult Mouse Brain.
Volume: 22
Issue: 8
Pages: 1974-1981
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Publication
22355785 | J:207277
 
First Author: Kunimoto H
Year: 2012
Journal: Sci Rep
Title: Tet2 disruption leads to enhanced self-renewal and altered differentiation of fetal liver hematopoietic stem cells.
Volume: 2
Pages: 273
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Publication
22981865 | J:191279
First Author: Kallin EM
Year: 2012
Journal: Mol Cell
Title: Tet2 facilitates the derepression of myeloid target genes during CEBP?-induced transdifferentiation of pre-B cells.
Volume: 48
Issue: 2
Pages: 266-76
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Publication
40500265 | J:389913
First Author: Rong K
Year: 2025
Journal: Bone Res
Title: Inflammatory macrophage-derived itaconate inhibits DNA demethylase TET2 to prevent excessive osteoclast activation in rheumatoid arthritis.
Volume: 13
Issue: 1
Pages: 60
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Publication
31484061 | J:280583
First Author: Ito K
Year: 2019
Journal: Cell Rep
Title: Non-catalytic Roles of Tet2 Are Essential to Regulate Hematopoietic Stem and Progenitor Cell Homeostasis.
Volume: 28
Issue: 10
Pages: 2480-2490.e4
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Publication
38168657 | J:344626
 
First Author: Shi Y
Year: 2024
Journal: Redox Biol
Title: Endothelial TET2 regulates the white adipose browning and metabolism via fatty acid oxidation in obesity.
Volume: 69
Pages: 103013
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Publication
26287468 | J:225970
First Author: Zhang Q
Year: 2015
Journal: Nature
Title: Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6.
Volume: 525
Issue: 7569
Pages: 389-393
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Publication
39234670 | J:360257
First Author: Polizio AH
Year: 2024
Journal: Circ Res
Title: Experimental TET2 Clonal Hematopoiesis Predisposes to Renal Hypertension Through an Inflammasome-Mediated Mechanism.
Volume: 135
Issue: 9
Pages: 933-950
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Publication
39627458 | J:359295
First Author: Gioulbasani M
Year: 2024
Journal: Commun Biol
Title: Concomitant loss of TET2 and TET3 results in T cell expansion and genomic instability in mice.
Volume: 7
Issue: 1
Pages: 1606
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Publication
26586431 | J:228945
First Author: Zhao Z
Year: 2015
Journal: Cell Rep
Title: Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice.
Volume: 13
Issue: 8
Pages: 1692-704
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Publication
24474761 | J:206652
First Author: Huang Y
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells.
Volume: 111
Issue: 4
Pages: 1361-6
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Publication
25263596 | J:215528
First Author: Hon GC
Year: 2014
Journal: Mol Cell
Title: 5mC oxidation by Tet2 modulates enhancer activity and timing of transcriptome reprogramming during differentiation.
Volume: 56
Issue: 2
Pages: 286-297
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Publication
21778364 | J:175793
First Author: Ito S
Year: 2011
Journal: Science
Title: Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.
Volume: 333
Issue: 6047
Pages: 1300-3
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Publication
35990681 | J:361753
 
First Author: ?ij? T
Year: 2022
Journal: Front Immunol
Title: TET proteins regulate T cell and iNKT cell lineage specification in a TET2 catalytic dependent manner.
Volume: 13
Pages: 940995
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Publication
30146412 | J:271506
First Author: Sun J
Year: 2018
Journal: Cell Stem Cell
Title: SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function.
Volume: 23
Issue: 3
Pages: 355-369.e9
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Publication
25601757 | J:219967
First Author: Wang Y
Year: 2015
Journal: Mol Cell
Title: WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation.
Volume: 57
Issue: 4
Pages: 662-673
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Publication
29467326 | J:330939
 
First Author: Palam LR
Year: 2018
Journal: JCI Insight
Title: Loss of epigenetic regulator TET2 and oncogenic KIT regulate myeloid cell transformation via PI3K pathway.
Volume: 3
Issue: 4
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Publication
37781816 | J:358011
First Author: Yalcinkaya M
Year: 2023
Journal: Circulation
Title: BRCC3-Mediated NLRP3 Deubiquitylation Promotes Inflammasome Activation and Atherosclerosis in Tet2 Clonal Hematopoiesis.
Volume: 148
Issue: 22
Pages: 1764-1777
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Publication
25501021 | J:250061
First Author: Muto H
Year: 2014
Journal: Blood Cancer J
Title: Reduced TET2 function leads to T-cell lymphoma with follicular helper T-cell-like features in mice.
Volume: 4
Issue: 12
Pages: e264
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Publication
16722336 | J:331042
First Author: Tang H
Year: 2006
Journal: Yi Chuan Xue Bao
Title: Cloning and expression analysis of a murine novel gene, Ayu17-449.
Volume: 33
Issue: 5
Pages: 413-9
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Publication
28813659 | J:253333
First Author: Pan W
Year: 2017
Journal: Immunity
Title: The DNA Methylcytosine Dioxygenase Tet2 Sustains Immunosuppressive Function of Tumor-Infiltrating Myeloid Cells to Promote Melanoma Progression.
Volume: 47
Issue: 2
Pages: 284-297.e5
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Publication
29275866 | J:253744
First Author: Kunimoto H
Year: 2018
Journal: Cancer Cell
Title: Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity.
Volume: 33
Issue: 1
Pages: 44-59.e8
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Publication
27869616 | J:239176
   
First Author: Lio CW
Year: 2016
Journal: Elife
Title: Tet2 and Tet3 cooperate with B-lineage transcription factors to regulate DNA modification and chromatin accessibility.
Volume: 5
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Publication
21295276 | J:168828
First Author: Koh KP
Year: 2011
Journal: Cell Stem Cell
Title: Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells.
Volume: 8
Issue: 2
Pages: 200-13
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Publication
28416650 | J:242004
First Author: Ma S
Year: 2017
Journal: J Exp Med
Title: Epigenetic regulator CXXC5 recruits DNA demethylase Tet2 to regulate TLR7/9-elicited IFN response in pDCs.
Volume: 214
Issue: 5
Pages: 1471-1491
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Publication
33090974 | J:331044
 
First Author: Cai Z
Year: 2021
Journal: J Clin Invest
Title: Hyperglycemia cooperates with Tet2 heterozygosity to induce leukemia driven by proinflammatory cytokine-induced lncRNA Morrbid.
Volume: 131
Issue: 1
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Publication
30274972 | J:268224
First Author: Dominguez PM
Year: 2018
Journal: Cancer Discov
Title: TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis.
Volume: 8
Issue: 12
Pages: 1632-1653
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Publication
41218172 | J:391221
First Author: Rondeau V
Year: 2026
Journal: Cancer Res
Title: Response to Immune Checkpoint Blockade Is Enhanced in the Presence of Hematopoietic TET2 Inactivation.
Volume: 86
Issue: 4
Pages: 845-857
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Publication
35697791 | J:326986
First Author: Wei Y
Year: 2022
Journal: Leukemia
Title: Cooperation between KDM6B overexpression and TET2 deficiency in the pathogenesis of chronic myelomonocytic leukemia.
Volume: 36
Issue: 8
Pages: 2097-2107
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Publication
25395421 | J:330937
First Author: Kameda T
Year: 2015
Journal: Blood
Title: Loss of TET2 has dual roles in murine myeloproliferative neoplasms: disease sustainer and disease accelerator.
Volume: 125
Issue: 2
Pages: 304-15
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Publication
29866713 | J:318890
First Author: Jin X
Year: 2018
Journal: Blood Adv
Title: Oncogenic N-Ras and Tet2 haploinsufficiency collaborate to dysregulate hematopoietic stem and progenitor cells.
Volume: 2
Issue: 11
Pages: 1259-1271
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Publication
38601144 | J:347082
 
First Author: Dennis E
Year: 2024
Journal: Front Immunol
Title: Loss of TET2 increases B-1 cell number and IgM production while limiting CDR3 diversity.
Volume: 15
Pages: 1380641
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Publication
34657351 | J:330934
First Author: Nguyen YTM
Year: 2021
Journal: Cancer Sci
Title: Tet2 deficiency in immune cells exacerbates tumor progression by increasing angiogenesis in a lung cancer model.
Volume: 112
Issue: 12
Pages: 4931-4943
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Publication
29858571 | J:266313
First Author: Yang R
Year: 2018
Journal: Nat Commun
Title: Tet1 and Tet2 maintain mesenchymal stem cell homeostasis via demethylation of the P2rX7 promoter.
Volume: 9
Issue: 1
Pages: 2143
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Publication
23453809 | J:198143
First Author: Piccolo FM
Year: 2013
Journal: Mol Cell
Title: Different roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EGC fusion.
Volume: 49
Issue: 6
Pages: 1023-33
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Publication
32572241 | J:297806
First Author: Tanaka S
Year: 2020
Journal: Nat Immunol
Title: Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity.
Volume: 21
Issue: 8
Pages: 950-961
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Publication
30526882 | J:271404
First Author: Cai Z
Year: 2018
Journal: Cell Stem Cell
Title: Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis.
Volume: 23
Issue: 6
Pages: 833-849.e5
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Publication
38561362 | J:373636
First Author: Zeng Q
Year: 2024
Journal: Nat Commun
Title: A negative feedback loop between TET2 and leptin in adipocyte regulates body weight.
Volume: 15
Issue: 1
Pages: 2825
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Publication
40111422 | J:366475
 
First Author: Zhang P
Year: 2025
Journal: J Clin Invest
Title: TP53 mutations and TET2 deficiency cooperate to drive leukemogenesis and establish an immunosuppressive environment.
Volume: 135
Issue: 10
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Publication
33853366 | J:330985
 
First Author: Yin M
Year: 2021
Journal: ASN Neuro
Title: LncRNA TUG1 Demethylated by TET2 Promotes NLRP3 Expression, Contributes to Cerebral Ischemia/Reperfusion Inflammatory Injury.
Volume: 13
Pages: 17590914211003247
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Publication
25862091 | J:229699
First Author: Ichiyama K
Year: 2015
Journal: Immunity
Title: The methylcytosine dioxygenase Tet2 promotes DNA demethylation and activation of cytokine gene expression in T cells.
Volume: 42
Issue: 4
Pages: 613-26
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