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Search results 1 to 100 out of 3242 for Thy1

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Type Details Score
Gene
Type: gene
Organism: Not Specified
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Gene
Type: gene
Organism: human
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Gene
Type: gene
Organism: frog, western clawed
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Gene
Type: gene
Organism: rat
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Gene
Type: gene
Organism: dog, domestic
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Gene
Type: gene
Organism: chimpanzee
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Gene
Type: gene
Organism: cattle
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Gene
Type: gene
Organism: chicken
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Gene
Type: gene
Organism: zebrafish
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Gene
Type: gene
Organism: macaque, rhesus
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Protein Domain
Type: Family
Description: Thy-1 membrane glycoprotein (also known as CD90) was identified as an activation-associated cell adhesion molecule on human dermal microvascular endothelial cells. Its cellular effects vary; however, it most often seems to affect cell-cell or cell-matrix interactions and cellular adhesion and migration [, ]. Thy-1 interacts with the leukocyte integrin Mac-1 and may play an important role in the regulation of leukocyte recruitment to sites of inflammation []. It also plays an important role in normal retinal development [].
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
First Author: Simon PD
Year: 1999
Journal: Brain Res Dev Brain Res
Title: Thy-1 is critical for normal retinal development.
Volume: 117
Issue: 2
Pages: 219-23
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Gene
Type: gene
Organism: human
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Publication
First Author: Woeller CF
Year: 2015
Journal: FASEB J
Title: Thy1 (CD90) controls adipogenesis by regulating activity of the Src family kinase, Fyn.
Volume: 29
Issue: 3
Pages: 920-31
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Publication
First Author: Paine A
Year: 2018
Journal: FASEB J
Title: Thy1 is a positive regulator of osteoblast differentiation and modulates bone homeostasis in obese mice.
Volume: 32
Issue: 6
Pages: 3174-3183
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Publication  
First Author: McCullough KM
Year: 2016
Journal: Nat Commun
Title: Molecular characterization of Thy1 expressing fear-inhibiting neurons within the basolateral amygdala.
Volume: 7
Pages: 13149
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Publication
First Author: Cohen PY
Year: 2009
Journal: Am J Respir Cell Mol Biol
Title: Thy1 up-regulates FasL expression in lung myofibroblasts via Src family kinases.
Volume: 40
Issue: 2
Pages: 231-8
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Publication
First Author: Koren E
Year: 2022
Journal: Nat Commun
Title: Thy1 marks a distinct population of slow-cycling stem cells in the mouse epidermis.
Volume: 13
Issue: 1
Pages: 4628
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Protein
Organism: Mus musculus/domesticus
Length: 162  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 162  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 125  
Fragment?: true
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Publication
First Author: Wetzel A
Year: 2004
Journal: J Immunol
Title: Human Thy-1 (CD90) on activated endothelial cells is a counterreceptor for the leukocyte integrin Mac-1 (CD11b/CD18).
Volume: 172
Issue: 6
Pages: 3850-9
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Publication  
First Author: Leyton L
Year: 2014
Journal: Adv Neurobiol
Title: Thy-1 modulates neurological cell-cell and cell-matrix interactions through multiple molecular interactions.
Volume: 8
Pages: 3-20
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Publication
First Author: Barker TH
Year: 2004
Journal: Exp Cell Res
Title: Thy-1 regulates fibroblast focal adhesions, cytoskeletal organization and migration through modulation of p190 RhoGAP and Rho GTPase activity.
Volume: 295
Issue: 2
Pages: 488-96
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Publication
First Author: Itami S
Year: 2011
Journal: Biol Reprod
Title: The roles of THY1 and integrin beta3 in cell adhesion during theca cell layer formation and the effect of follicle-stimulating hormone on THY1 and integrin beta3 localization in mouse ovarian follicles.
Volume: 84
Issue: 5
Pages: 986-95
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Publication  
First Author: Gilman TL
Year: 2018
Journal: Neurobiol Learn Mem
Title: Basolateral amygdala Thy1-expressing neurons facilitate the inhibition of contextual fear during consolidation, reconsolidation, and extinction.
Volume: 155
Pages: 498-507
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Publication
First Author: Chen SJ
Year: 2006
Journal: Immunol Lett
Title: Kinetics of adaptive immunity to Haemophilus influenzae type b meningitis in transgenic mice: evidence from diverse expression of double T1/T2 transgenes and Th1/Th2-related cytokines.
Volume: 105
Issue: 1
Pages: 6-15
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Publication  
First Author: Marangoni RG
Year: 2022
Journal: JCI Insight
Title: Thy-1 plays a pathogenic role and is a potential biomarker for skin fibrosis in scleroderma.
Volume: 7
Issue: 19
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Publication
First Author: Mix MR
Year: 2025
Journal: Cell Rep
Title: Repetitive antigen stimulation in the periphery dictates the composition and recall responses of brain-resident memory CD8(+) T??cells.
Volume: 44
Issue: 2
Pages: 115247
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Publication
First Author: Pritzl CJ
Year: 2023
Journal: Nat Commun
Title: IKK2/NFkB signaling controls lung resident CD8(+) T cell memory during influenza infection.
Volume: 14
Issue: 1
Pages: 4331
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Publication
First Author: Messmer JM
Year: 2024
Journal: Immunity
Title: T lymphocyte recruitment to melanoma brain tumors depends on distinct venous vessels.
Volume: 57
Issue: 11
Pages: 2688-2703.e11
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Publication
First Author: Schietinger A
Year: 2016
Journal: Immunity
Title: Tumor-Specific T Cell Dysfunction Is a Dynamic Antigen-Driven Differentiation Program Initiated Early during Tumorigenesis.
Volume: 45
Issue: 2
Pages: 389-401
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Publication
First Author: Voehringer D
Year: 2008
Journal: J Immunol
Title: Homeostasis and effector function of lymphopenia-induced "memory-like" T cells in constitutively T cell-depleted mice.
Volume: 180
Issue: 7
Pages: 4742-53
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Publication
First Author: W?thrich M
Year: 2012
Journal: Infect Immun
Title: Limited model antigen expression by transgenic fungi induces disparate fates during differentiation of adoptively transferred T cell receptor transgenic CD4+ T cells: robust activation and proliferation with weak effector function during recall.
Volume: 80
Issue: 2
Pages: 787-97
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Publication
First Author: Effern M
Year: 2020
Journal: Immunity
Title: Adoptive T Cell Therapy Targeting Different Gene Products Reveals Diverse and Context-Dependent Immune Evasion in Melanoma.
Volume: 53
Issue: 3
Pages: 564-580.e9
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Publication
First Author: Mortazavi Farsani SS
Year: 2025
Journal: Cell Metab
Title: Pyruvate kinase M2 activation reprograms mitochondria in CD8 T cells, enhancing effector functions and efficacy of anti-PD1 therapy.
Volume: 37
Issue: 6
Pages: 1294-1310.e7
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Publication
First Author: Yang W
Year: 2024
Journal: Nat Commun
Title: Calcium nanoparticles target and activate T cells to enhance anti-tumor function.
Volume: 15
Issue: 1
Pages: 10095
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Publication
First Author: Tcyganov EN
Year: 2022
Journal: Cancer Cell
Title: Peroxynitrite in the tumor microenvironment changes the profile of antigens allowing escape from cancer immunotherapy.
Volume: 40
Issue: 10
Pages: 1173-1189.e6
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Publication
First Author: Basak D
Year: 2026
Journal: EMBO Rep
Title: S1P-S1PR1 signaling impairs CD8(+) T cell metabolism and effector function in tumors.
Volume: 27
Issue: 8
Pages: 2000-2028
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Publication
First Author: Azzolino V
Year: 2021
Journal: J Invest Dermatol
Title: Jak Inhibitors Reverse Vitiligo in Mice but Do Not Deplete Skin Resident Memory T Cells.
Volume: 141
Issue: 1
Pages: 182-184.e1
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Publication
First Author: Wang Y
Year: 2025
Journal: Nat Cell Biol
Title: Tumour interstitial fluid-enriched phosphoethanolamine suppresses T cell function.
Volume: 27
Issue: 5
Pages: 835-846
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Publication
First Author: Morgado-C??ceres P
Year: 2026
Journal: Oncoimmunology
Title: DNA prime and peptide boost immunization elicits robust neoantigen-specific CD8 (+) T cell responses and therapeutic protection in mouse tumor models.
Volume: 15
Issue: 1
Pages: 2606497
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Publication
First Author: Zhou X
Year: 2025
Journal: Cell Rep Med
Title: Potentiating anti-tumor immunity by re-engaging immune synapse molecules.
Volume: 6
Issue: 3
Pages: 101975
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Publication
First Author: Srivastava J
Year: 2025
Journal: Cancer Res
Title: Blocking Nitrosylation Induces Immunogenic Cell Death by Sensitizing NRAS-Mutant Melanoma to MEK Inhibitors.
Volume: 85
Issue: 12
Pages: 2268-2287
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Publication
First Author: Magno JC
Year: 2026
Journal: Cancer Res
Title: Engineering T Cells with a Tumor-Reactive Chimeric T-cell Receptor Reduces Exhaustion and Promotes Persistence to Elicit Enhanced Antitumor Responses.
Volume: 86
Issue: 11
Pages: 2688-2702
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Publication
First Author: Zhang FQ
Year: 2025
Journal: Cell Rep Med
Title: Zeaxanthin augments CD8(+) effector T cell function and immunotherapy efficacy.
Volume: 6
Issue: 9
Pages: 102324
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Publication  
First Author: Gellert S
Year: 2026
Journal: Front Immunol
Title: Oncolytic virotherapy counteracts the selection of IFN-unresponsive cancer cells post-immunotherapy but is limited by the emergence of dedifferentiated cancer cells.
Volume: 17
Pages: 1875225
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Publication
First Author: Effern M
Year: 2022
Journal: STAR Protoc
Title: CRISPitope: A generic platform to model target antigens for adoptive T?cell transfer therapy in mouse tumor models.
Volume: 3
Issue: 1
Pages: 101038
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Publication
First Author: Hammons JN
Year: 2026
Journal: Hepatology
Title: Tumor site influences efficacy of MEKi and immunotherapy combinations in a preclinical model of cholangiocarcinoma.
Volume: 84
Issue: 1
Pages: 20-36
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Publication
First Author: Misumi I
Year: 2019
Journal: Cell Rep
Title: Obesity Expands a Distinct Population of T Cells in Adipose Tissue and Increases Vulnerability to Infection.
Volume: 27
Issue: 2
Pages: 514-524.e5
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Publication  
First Author: Zaleski MB
Year: 1975
Journal: Immunogenetics
Title: Immune response of mice to the Thy-1.1 antigen: effect of the Ir-5 alleles studies in 129/J and B10.129(6M) mice.
Volume: 2
Pages: 241-8
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Publication
First Author: Ranheim EA
Year: 2004
Journal: Autoimmunity
Title: Selection of aberrant class II restricted CD8+ T cells in NOD mice expressing a glutamic acid decarboxylase (GAD)65-specific T cell receptor transgene.
Volume: 37
Issue: 8
Pages: 555-67
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Publication  
First Author: Detr??s Rom??n CR
Year: 2024
Journal: J Immunother Cancer
Title: Vaccination generates functional progenitor tumor-specific CD8 T cells and long-term tumor control.
Volume: 12
Issue: 10
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Publication  
First Author: Ren Y
Year: 2026
Journal: J Immunol
Title: eEF2K promotes immune evasion in melanoma via Cyclin D1-mediated stabilization of PD-L1.
Volume: 215
Issue: 2
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Publication  
First Author: Raff MC
Year: 1971
Journal: Transplant Rev
Title: Surface antigenic markers for distinguishing T and B lymphocytes in mice.
Volume: 6
Pages: 52-80
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Publication
First Author: Li Y
Year: 1999
Journal: Invest Ophthalmol Vis Sci
Title: Experimental induction of retinal ganglion cell death in adult mice.
Volume: 40
Issue: 5
Pages: 1004-8
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Publication
First Author: Andreata F
Year: 2024
Journal: Cell
Title: Therapeutic potential of co-signaling receptor modulation in hepatitis B.
Volume: 187
Issue: 15
Pages: 4078-4094.e21
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Publication
First Author: Xu Z
Year: 2022
Journal: Nature
Title: Anatomically distinct fibroblast subsets determine skin autoimmune patterns.
Volume: 601
Issue: 7891
Pages: 118-124
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Publication
First Author: Zhang R
Year: 2025
Journal: Sci Adv
Title: USP30 inhibition augments mitophagy to prevent T cell exhaustion.
Volume: 11
Issue: 33
Pages: eadv6902
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Publication  
First Author: Clarkson BD
Year: 2017
Journal: Sci Rep
Title: CCR7 deficient inflammatory Dendritic Cells are retained in the Central Nervous System.
Volume: 7
Pages: 42856
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Publication
First Author: Huang W
Year: 2014
Journal: J Immunol
Title: IL-2-inducible T cell kinase tunes T regulatory cell development and is required for suppressive function.
Volume: 193
Issue: 5
Pages: 2267-72
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Publication
First Author: Lee SY
Year: 2013
Journal: J Immunol
Title: The influence of T cell Ig mucin-3 signaling on central nervous system autoimmune disease is determined by the effector function of the pathogenic T cells.
Volume: 190
Issue: 10
Pages: 4991-9
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Publication
First Author: Zimmermannova O
Year: 2023
Journal: Sci Immunol
Title: Restoring tumor immunogenicity with dendritic cell reprogramming.
Volume: 8
Issue: 85
Pages: eadd4817
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Publication
First Author: Ando Y
Year: 2025
Journal: Oncoimmunology
Title: Hyperdifferentiated murine melanoma cells promote adaptive anti-tumor immunity but activate the immune checkpoint system.
Volume: 14
Issue: 1
Pages: 2437211
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Publication
First Author: Choi BK
Year: 2018
Journal: Eur J Immunol
Title: RELT negatively regulates the early phase of the T-cell response in mice.
Volume: 48
Issue: 10
Pages: 1739-1749
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Publication
First Author: Hernandez R
Year: 2021
Journal: Cancer Immunol Immunother
Title: Sustained IL-2R signaling of limited duration by high-dose mIL-2/mCD25 fusion protein amplifies tumor-reactive CD8(+) T cells to enhance antitumor immunity.
Volume: 70
Issue: 4
Pages: 909-921
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Publication
First Author: Wang L
Year: 2009
Journal: J Immunol
Title: Epidermal Langerhans cells are not required for UV-induced immunosuppression.
Volume: 183
Issue: 9
Pages: 5548-53
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Publication
First Author: Zaleski M
Year: 1974
Journal: J Immunol
Title: Immune response of mice to Thy-1. 1 antigen: genetic control by alleles at the Ir-5 locus loosely linked to the H-2 complex.
Volume: 113
Issue: 4
Pages: 1170-7
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Publication
First Author: Jayant K
Year: 2019
Journal: Cell Rep
Title: Flexible Nanopipettes for Minimally Invasive Intracellular Electrophysiology In?Vivo.
Volume: 26
Issue: 1
Pages: 266-278.e5
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Publication
First Author: Alamir H
Year: 2025
Journal: Sci Signal
Title: TIM3 is a context-dependent coregulator of cytotoxic T cell function.
Volume: 18
Issue: 905
Pages: eadk4594
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Publication
First Author: Liu T
Year: 2023
Journal: Cell Insight
Title: Cannabinoid receptor 2 signal promotes type 2 immunity in the lung.
Volume: 2
Issue: 5
Pages: 100124
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Publication
First Author: REIF AE
Year: 1964
Journal: J Exp Med
Title: THE AKR THYMIC ANTIGEN AND ITS DISTRIBUTION IN LEUKEMIAS AND NERVOUS TISSUES.
Volume: 120
Issue: 3
Pages: 413-33
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Publication
First Author: Reif AE
Year: 1966
Journal: Nature
Title: Mouse thymic iso-antigens.
Volume: 209
Issue: 5022
Pages: 521-3
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Publication
First Author: Chen TT
Year: 2005
Journal: J Exp Med
Title: TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis.
Volume: 202
Issue: 7
Pages: 955-65
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Publication
First Author: Booty MG
Year: 2022
Journal: J Immunol
Title: Microfluidic Squeezing Enables MHC Class I Antigen Presentation by Diverse Immune Cells to Elicit CD8(+) T Cell Responses with Antitumor Activity.
Volume: 208
Issue: 4
Pages: 929-940
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Publication
First Author: Beziaud L
Year: 2023
Journal: Cell Stem Cell
Title: IFN?-induced stem-like state of cancer cells as a driver of metastatic progression following immunotherapy.
Volume: 30
Issue: 6
Pages: 818-831.e6
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Publication
First Author: W?thrich M
Year: 2005
Journal: J Immunol
Title: IL-12 is required for induction but not maintenance of protective, memory responses to Blastomyces dermatitidis: implications for vaccine development in immune-deficient hosts.
Volume: 175
Issue: 8
Pages: 5288-97
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Publication
First Author: Lee J
Year: 2023
Journal: Cancer Discov
Title: Sex-Biased T-cell Exhaustion Drives Differential Immune Responses in Glioblastoma.
Volume: 13
Issue: 9
Pages: 2090-2105
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Publication
First Author: Weng CH
Year: 2026
Journal: Cell Rep
Title: Tumor-intrinsic expression of signal regulatory protein ?? contributes to the suppression of anti-tumor immune responses.
Volume: 45
Issue: 6
Pages: 117443
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Publication
First Author: Wittling MC
Year: 2026
Journal: Cancer Immunol Res
Title: T-cell Priming by High-Avidity Neoantigens in Lymph Nodes Augments Adoptive Immunotherapy.
Volume: 14
Issue: 3
Pages: 463-477
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Publication
First Author: Ma X
Year: 2021
Journal: Cell Metab
Title: CD36-mediated ferroptosis dampens intratumoral CD8(+) T?cell effector function and impairs their antitumor ability.
Volume: 33
Issue: 5
Pages: 1001-1012.e5
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Publication
First Author: Sharma J
Year: 2024
Journal: J Leukoc Biol
Title: E3 ubiquitin ligase CBLB regulates innate immune responses and bacterial dissemination during nontuberculous mycobacteria infection.
Volume: 115
Issue: 6
Pages: 1118-1130
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Publication
First Author: Borst L
Year: 2022
Journal: Int J Cancer
Title: NKG2A is a late immune checkpoint on CD8 T cells and marks repeated stimulation and cell division.
Volume: 150
Issue: 4
Pages: 688-704
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Publication
First Author: Yan H
Year: 2023
Journal: iScience
Title: The transcription factor IRF4 determines the anti-tumor immunity of CD8(+) T?cells.
Volume: 26
Issue: 11
Pages: 108087
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Publication
First Author: Ulibarri MR
Year: 2024
Journal: Cell Rep
Title: Epithelial organoid supports resident memory CD8 T?cell differentiation.
Volume: 43
Issue: 8
Pages: 114621
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Publication
First Author: Chakraborty P
Year: 2019
Journal: J Biol Chem
Title: Thioredoxin-1 improves the immunometabolic phenotype of antitumor T cells.
Volume: 294
Issue: 23
Pages: 9198-9212
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Publication
First Author: Molodtsov AK
Year: 2021
Journal: Immunity
Title: Resident memory CD8(+) T?cells in regional lymph nodes mediate immunity to metastatic melanoma.
Volume: 54
Issue: 9
Pages: 2117-2132.e7
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Publication  
First Author: Snell GD
Year: 1971
Journal: Transplant Proc
Title: The histocompatibility systems
Volume: 3
Pages: 1133-1138
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Publication
First Author: Hsu M
Year: 2019
Journal: Nat Commun
Title: Neuroinflammation-induced lymphangiogenesis near the cribriform plate contributes to drainage of CNS-derived antigens and immune cells.
Volume: 10
Issue: 1
Pages: 229
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Publication
First Author: Mandarano AH
Year: 2023
Journal: Cell Rep
Title: DRAK2 contributes to type 1 diabetes by negatively regulating IL-2 sensitivity to alter regulatory T?cell development.
Volume: 42
Issue: 2
Pages: 112106
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Publication
First Author: Chatterjee S
Year: 2014
Journal: Cancer Res
Title: Reducing CD73 expression by IL1?-Programmed Th17 cells improves immunotherapeutic control of tumors.
Volume: 74
Issue: 21
Pages: 6048-59
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Publication
First Author: Jasnow AM
Year: 2013
Journal: J Neurosci
Title: Thy1-expressing neurons in the basolateral amygdala may mediate fear inhibition.
Volume: 33
Issue: 25
Pages: 10396-404
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Publication
First Author: Klebanoff CA
Year: 2013
Journal: J Exp Med
Title: Retinoic acid controls the homeostasis of pre-cDC-derived splenic and intestinal dendritic cells.
Volume: 210
Issue: 10
Pages: 1961-76
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Publication
First Author: Oberholtzer N
Year: 2024
Journal: Sci Adv
Title: H(2)S-Prdx4 axis mitigates Golgi stress to bolster tumor-reactive T cell immunotherapeutic response.
Volume: 10
Issue: 46
Pages: eadp1152
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Publication
First Author: Badrinath S
Year: 2022
Journal: Nature
Title: A vaccine targeting resistant tumours by dual T cell plus NK cell attack.
Volume: 606
Issue: 7916
Pages: 992-998
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Publication
First Author: Krieg C
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Improved IL-2 immunotherapy by selective stimulation of IL-2 receptors on lymphocytes and endothelial cells.
Volume: 107
Issue: 26
Pages: 11906-11
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Publication
First Author: Brinkman CC
Year: 2013
Journal: J Immunol
Title: Peripheral tissue homing receptors enable T cell entry into lymph nodes and affect the anatomical distribution of memory cells.
Volume: 191
Issue: 5
Pages: 2412-25
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Publication
First Author: Torres-Mejia E
Year: 2025
Journal: Cancer Immunol Res
Title: Lung Cancer-Intrinsic SOX2 Expression Mediates Resistance to Checkpoint Blockade Therapy by Inducing Treg-Dependent CD8+ T-cell Exclusion.
Volume: 13
Issue: 4
Pages: 496-516
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Publication
First Author: Nanjappa SG
Year: 2017
Journal: PLoS Pathog
Title: Antifungal Tc17 cells are durable and stable, persisting as long-lasting vaccine memory without plasticity towards IFN? cells.
Volume: 13
Issue: 5
Pages: e1006356
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