| Type | Details | Score | 
          
              | Gene | 
              
                | Type: | gene |  
                | Organism: | human |  | • • • • • | 
          
              | Gene | 
              
                | Type: | gene |  
                | Organism: | frog, western clawed |  | • • • • • | 
          
              | Gene | 
              
                | Type: | gene |  
                | Organism: | dog, domestic |  | • • • • • | 
          
              | Gene |  | • • • • • | 
          
              | Gene | 
              
                | Type: | gene |  
                | Organism: | chimpanzee |  | • • • • • | 
          
              | Gene | 
              
                | Type: | gene |  
                | Organism: | cattle |  | • • • • • | 
          
              | Gene | 
              
                | Type: | gene |  
                | Organism: | macaque, rhesus |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Domain | 
              
                | Type: | Family |  
                | Description: | Toll-like receptor 6 (TLR6) participates in the innate immune response to Gram-positive bacteria and fungi. TLRs recognize specific molecular patterns present only in micro-organisms. TLR1 and TLR6 are involved in the discrimination of a subtle difference between triacyl and diacyl lipopeptides through interaction with TLR2 []. Cooperatively with TLR2, TLR6 recognises mycoplasmal macrophage-activating lipopeptide-2 (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and Borrelia burgdorferi outer surface protein A lipoprotein (OspA-L) []. TLR6 acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response []. |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Takeuchi O |  
                | Year: | 1999 |  
                | Journal: | Gene |  
                | Title: | TLR6: A novel member of an expanding toll-like receptor family. |  
                | Volume: | 231 |  
                | Issue: | 1-2 |  
                | Pages: | 59-65 |  | • • • • • | 
          
              | Protein | 
              
                | Organism: | Mus musculus/domesticus |  
                | Length: | 806  |  
                | Fragment?: | false |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Sugawara I |  
                | Year: | 2003 |  
                | Journal: | Microbiol Immunol |  
                | Title: | Mycobacterial infection in TLR2 and TLR6 knockout mice. |  
                | Volume: | 47 |  
                | Issue: | 5 |  
                | Pages: | 327-36 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Curtiss LK |  
                | Year: | 2012 |  
                | Journal: | J Lipid Res |  
                | Title: | Atherosclerosis induced by endogenous and exogenous toll-like receptor (TLR)1 or TLR6 agonists. |  
                | Volume: | 53 |  
                | Issue: | 10 |  
                | Pages: | 2126-32 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Chen J |  
                | Year: | 2015 |  
                | Journal: | PLoS Pathog |  
                | Title: | Activation of TLR2 and TLR6 by Dengue NS1 Protein and Its Implications in the Immunopathogenesis of Dengue Virus Infection. |  
                | Volume: | 11 |  
                | Issue: | 7 |  
                | Pages: | e1005053 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Moreira AP |  
                | Year: | 2011 |  
                | Journal: | J Clin Invest |  
                | Title: | The protective role of TLR6 in a mouse model of asthma is mediated by IL-23 and IL-17A. |  
                | Volume: | 121 |  
                | Issue: | 11 |  
                | Pages: | 4420-32 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Bulut Y |  
                | Year: | 2001 |  
                | Journal: | J Immunol |  
                | Title: | Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling. |  
                | Volume: | 167 |  
                | Issue: | 2 |  
                | Pages: | 987-94 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Miranda-Hernandez S |  
                | Year: | 2011 |  
                | Journal: | J Immunol |  
                | Title: | Role for MyD88, TLR2 and TLR9 but not TLR1, TLR4 or TLR6 in experimental autoimmune encephalomyelitis. |  
                | Volume: | 187 |  
                | Issue: | 2 |  
                | Pages: | 791-804 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Takeda K |  
                | Year: | 2002 |  
                | Journal: | J Endotoxin Res |  
                | Title: | Recognition of lipopeptides by Toll-like receptors. |  
                | Volume: | 8 |  
                | Issue: | 6 |  
                | Pages: | 459-63 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Gomes MT |  
                | Year: | 2016 |  
                | Journal: | J Leukoc Biol |  
                | Title: | TLR9 is required for MAPK/NF-κB activation but does not cooperate with TLR2 or TLR6 to induce host resistance to Brucella abortus. |  
                | Volume: | 99 |  
                | Issue: | 5 |  
                | Pages: | 771-80 |  | • • • • • | 
          
              | Protein | 
              
                | Organism: | Mus musculus/domesticus |  
                | Length: | 102  |  
                | Fragment?: | true |  | • • • • • | 
          
              | Protein | 
              
                | Organism: | Mus musculus/domesticus |  
                | Length: | 795  |  
                | Fragment?: | false |  | • • • • • | 
          
              | Protein | 
              
                | Organism: | Mus musculus/domesticus |  
                | Length: | 806  |  
                | Fragment?: | false |  | • • • • • | 
          
              | Protein | 
              
                | Organism: | Mus musculus/domesticus |  
                | Length: | 806  |  
                | Fragment?: | false |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Jiang Z |  
                | Year: | 2006 |  
                | Journal: | Proc Natl Acad Sci U S A |  
                | Title: | Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis. |  
                | Volume: | 103 |  
                | Issue: | 29 |  
                | Pages: | 10961-6 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Takeuchi O |  
                | Year: | 2001 |  
                | Journal: | Int Immunol |  
                | Title: | Discrimination of bacterial lipoproteins by Toll-like receptor 6. |  
                | Volume: | 13 |  
                | Issue: | 7 |  
                | Pages: | 933-40 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Takeuchi O |  
                | Year: | 2002 |  
                | Journal: | J Immunol |  
                | Title: | Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins. |  
                | Volume: | 169 |  
                | Issue: | 1 |  
                | Pages: | 10-4 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Fong DJ |  
                | Year: | 2010 |  
                | Journal: | Immunology |  
                | Title: | Toll-like receptor 6 drives interleukin-17A expression during experimental hypersensitivity pneumonitis. |  
                | Volume: | 130 |  
                | Issue: | 1 |  
                | Pages: | 125-36 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Kim JH |  
                | Year: | 2020 |  
                | Journal: | Cancer Prev Res (Phila) |  
                | Title: | Toll-like Receptor-6 Signaling Prevents Inflammation and Impacts Composition of the Microbiota During Inflammation-Induced Colorectal Cancer. |  
                | Volume: | 13 |  
                | Issue: | 1 |  
                | Pages: | 25-40 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Kang JY |  
                | Year: | 2009 |  
                | Journal: | Immunity |  
                | Title: | Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer. |  
                | Volume: | 31 |  
                | Issue: | 6 |  
                | Pages: | 873-84 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Ozinsky A |  
                | Year: | 2000 |  
                | Journal: | Proc Natl Acad Sci U S A |  
                | Title: | The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. |  
                | Volume: | 97 |  
                | Issue: | 25 |  
                | Pages: | 13766-71 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Mattos KA |  
                | Year: | 2010 |  
                | Journal: | J Leukoc Biol |  
                | Title: | Lipid droplet formation in leprosy: Toll-like receptor-regulated organelles involved in eicosanoid formation and Mycobacterium leprae pathogenesis. |  
                | Volume: | 87 |  
                | Issue: | 3 |  
                | Pages: | 371-84 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Liu S |  
                | Year: | 2012 |  
                | Journal: | J Immunol |  
                | Title: | TLR2 is a primary receptor for Alzheimer's amyloid β peptide to trigger neuroinflammatory activation. |  
                | Volume: | 188 |  
                | Issue: | 3 |  
                | Pages: | 1098-107 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Drage MG |  
                | Year: | 2009 |  
                | Journal: | Cell Immunol |  
                | Title: | TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis. |  
                | Volume: | 258 |  
                | Issue: | 1 |  
                | Pages: | 29-37 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Albiger B |  
                | Year: | 2007 |  
                | Journal: | Cell Microbiol |  
                | Title: | Toll-like receptor 9 acts at an early stage in host defence against pneumococcal infection. |  
                | Volume: | 9 |  
                | Issue: | 3 |  
                | Pages: | 633-44 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Nicolle D |  
                | Year: | 2004 |  
                | Journal: | Infect Immun |  
                | Title: | Long-term control of Mycobacterium bovis BCG infection in the absence of Toll-like receptors (TLRs): investigation of TLR2-, TLR6-, or TLR2-TLR4-deficient mice. |  
                | Volume: | 72 |  
                | Issue: | 12 |  
                | Pages: | 6994-7004 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Ammerdorffer A |  
                | Year: | 2015 |  
                | Journal: | J Infect Dis |  
                | Title: | Recognition of Coxiella burnetii by toll-like receptors and nucleotide-binding oligomerization domain-like receptors. |  
                | Volume: | 211 |  
                | Issue: | 6 |  
                | Pages: | 978-87 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | de Almeida LA |  
                | Year: | 2013 |  
                | Journal: | Infect Immun |  
                | Title: | Toll-like receptor 6 plays an important role in host innate resistance to Brucella abortus infection in mice. |  
                | Volume: | 81 |  
                | Issue: | 5 |  
                | Pages: | 1654-62 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Chang S |  
                | Year: | 2007 |  
                | Journal: | J Leukoc Biol |  
                | Title: | Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins. |  
                | Volume: | 82 |  
                | Issue: | 3 |  
                | Pages: | 479-87 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Marinho FA |  
                | Year: | 2013 |  
                | Journal: | Eur J Immunol |  
                | Title: | Toll-like receptor 6 senses Mycobacterium avium and is required for efficient control of mycobacterial infection. |  
                | Volume: | 43 |  
                | Issue: | 9 |  
                | Pages: | 2373-85 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Oosting M |  
                | Year: | 2011 |  
                | Journal: | PLoS One |  
                | Title: | TLR1/TLR2 heterodimers play an important role in the recognition of Borrelia spirochetes. |  
                | Volume: | 6 |  
                | Issue: | 10 |  
                | Pages: | e25998 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Ray A |  
                | Year: | 2005 |  
                | Journal: | Immunology |  
                | Title: | Porin of Shigella dysenteriae enhances Toll-like receptors 2 and 6 of mouse peritoneal B-2 cells and induces the expression of immunoglobulin M, immunoglobulin G2a and immunoglobulin A. |  
                | Volume: | 114 |  
                | Issue: | 1 |  
                | Pages: | 94-100 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Riccioli A |  
                | Year: | 2006 |  
                | Journal: | J Immunol |  
                | Title: | Sertoli cells initiate testicular innate immune responses through TLR activation. |  
                | Volume: | 177 |  
                | Issue: | 10 |  
                | Pages: | 7122-30 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Owens AP 3rd |  
                | Year: | 2012 |  
                | Journal: | J Clin Invest |  
                | Title: | Monocyte tissue factor-dependent activation of coagulation in hypercholesterolemic mice and monkeys is inhibited by simvastatin. |  
                | Volume: | 122 |  
                | Issue: | 2 |  
                | Pages: | 558-68 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Leng CH |  
                | Year: | 2010 |  
                | Journal: | Mol Immunol |  
                | Title: | A recombinant lipoprotein containing an unsaturated fatty acid activates NF-kappaB through the TLR2 signaling pathway and induces a differential gene profile from a synthetic lipopeptide. |  
                | Volume: | 47 |  
                | Issue: | 11-12 |  
                | Pages: | 2015-21 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Quesniaux VJ |  
                | Year: | 2004 |  
                | Journal: | J Immunol |  
                | Title: | Toll-like receptor 2 (TLR2)-dependent-positive and TLR2-independent-negative regulation of proinflammatory cytokines by mycobacterial lipomannans. |  
                | Volume: | 172 |  
                | Issue: | 7 |  
                | Pages: | 4425-34 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Henneke P |  
                | Year: | 2001 |  
                | Journal: | J Immunol |  
                | Title: | Novel engagement of CD14 and multiple toll-like receptors by group B streptococci. |  
                | Volume: | 167 |  
                | Issue: | 12 |  
                | Pages: | 7069-76 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Hume DA |  
                | Year: | 2001 |  
                | Journal: | BMC Immunol |  
                | Title: | Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state. |  
                | Volume: | 2 |  
                |  |  
                | Pages: | 11 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Vinnakota K |  
                | Year: | 2013 |  
                | Journal: | Neuro Oncol |  
                | Title: | Toll-like receptor 2 mediates microglia/brain macrophage MT1-MMP expression and glioma expansion. |  
                | Volume: | 15 |  
                | Issue: | 11 |  
                | Pages: | 1457-68 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Ray A |  
                | Year: | 2004 |  
                | Journal: | Mol Immunol |  
                | Title: | Up-regulation of CD80-CD86 and IgA on mouse peritoneal B-1 cells by porin of Shigella dysenteriae is Toll-like receptors 2 and 6 dependent. |  
                | Volume: | 41 |  
                | Issue: | 12 |  
                | Pages: | 1167-75 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Biswas S |  
                | Year: | 2017 |  
                | Journal: | Circ Res |  
                | Title: | TLR2 Plays a Key Role in Platelet Hyperreactivity and Accelerated Thrombosis Associated With Hyperlipidemia. |  
                | Volume: | 121 |  
                | Issue: | 8 |  
                | Pages: | 951-962 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Kim S |  
                | Year: | 2009 |  
                | Journal: | Nature |  
                | Title: | Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis. |  
                | Volume: | 457 |  
                | Issue: | 7225 |  
                | Pages: | 102-6 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Murawski MR |  
                | Year: | 2009 |  
                | Journal: | J Virol |  
                | Title: | Respiratory syncytial virus activates innate immunity through Toll-like receptor 2. |  
                | Volume: | 83 |  
                | Issue: | 3 |  
                | Pages: | 1492-500 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Abplanalp AL |  
                | Year: | 2009 |  
                | Journal: | PLoS One |  
                | Title: | TLR-dependent control of Francisella tularensis infection and host inflammatory responses. |  
                | Volume: | 4 |  
                | Issue: | 11 |  
                | Pages: | e7920 |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | Mus caroli |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | Mus pahari |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | Mus spretus |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Siggs OM |  
                | Year: | 2009 |  
                | Journal: | MGI Direct Data Submission |  
                | Title: | Recored for "m2sd1", updated February 2, 2009 |  
                |  |  
                |  |  
                |  |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Siggs OM |  
                | Year: | 2009 |  
                | Journal: | MGI Direct Data Submission |  
                | Title: | Record for "m2sd2", updated February 2, 2009 |  
                |  |  
                |  |  
                |  |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Siggs OM |  
                | Year: | 2009 |  
                | Journal: | MGI Direct Data Submission |  
                | Title: | Record for "m2sd3", updated February 2, 2009 |  
                |  |  
                |  |  
                |  |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Buwitt-Beckmann U |  
                | Year: | 2005 |  
                | Journal: | Eur J Immunol |  
                | Title: | Toll-like receptor 6-independent signaling by diacylated lipopeptides. |  
                | Volume: | 35 |  
                | Issue: | 1 |  
                | Pages: | 282-9 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:5751172 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2016-03-07 |  
                | Strength: | Not Specified |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1603915 |  
                |  |  
                | Stage: | TS15 |  
                | Assay Id: | MGI:5751181 |  
                | Age: | embryonic day 9.5 |  
                | Image: | 5 |  
                |  |  
                | Specimen Label: | Dnmt3b-/- |  
                |  |  
                | Specimen Num: | 1 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:5751172 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2016-03-07 |  
                | Strength: | Not Specified |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1603915 |  
                |  |  
                | Stage: | TS15 |  
                | Assay Id: | MGI:5751181 |  
                | Age: | embryonic day 9.5 |  
                | Image: | 5 |  
                |  |  
                | Specimen Label: | Dnmt3a-/- |  
                |  |  
                | Specimen Num: | 2 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:5751172 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2016-03-07 |  
                | Strength: | Not Specified |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1603915 |  
                |  |  
                | Stage: | TS15 |  
                | Assay Id: | MGI:5751181 |  
                | Age: | embryonic day 9.5 |  
                | Image: | 5 |  
                |  |  
                | Specimen Label: | WT |  
                |  |  
                | Specimen Num: | 3 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:5751587 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2016-03-10 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1691018 |  
                |  |  
                | Stage: | TS18 |  
                | Assay Id: | MGI:5751719 |  
                | Age: | embryonic day 11.0 |  
                |  |  
                |  |  
                | Specimen Label: | E11 |  
                | Detected: | true |  
                | Specimen Num: | 1 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:5751587 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2016-03-10 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1754421 |  
                |  |  
                | Stage: | TS21 |  
                | Assay Id: | MGI:5751719 |  
                | Age: | embryonic day 13.0 |  
                |  |  
                |  |  
                | Specimen Label: | E13 |  
                | Detected: | true |  
                | Specimen Num: | 2 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:5751587 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2016-03-10 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1754423 |  
                |  |  
                | Stage: | TS23 |  
                | Assay Id: | MGI:5751719 |  
                | Age: | embryonic day 15.0 |  
                |  |  
                |  |  
                | Specimen Label: | E15 |  
                | Detected: | true |  
                | Specimen Num: | 3 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:5751587 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2016-03-10 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1754426 |  
                |  |  
                | Stage: | TS26 |  
                | Assay Id: | MGI:5751719 |  
                | Age: | embryonic day 19.0 |  
                |  |  
                |  |  
                | Specimen Label: | E19 |  
                | Detected: | true |  
                | Specimen Num: | 4 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:5751587 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2016-03-10 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1754427 |  
                |  |  
                | Stage: | TS27 |  
                | Assay Id: | MGI:5751719 |  
                | Age: | postnatal day 2 |  
                |  |  
                |  |  
                | Specimen Label: | P2 |  
                | Detected: | true |  
                | Specimen Num: | 5 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:5751587 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2016-03-10 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1754428 |  
                |  |  
                | Stage: | TS28 |  
                | Assay Id: | MGI:5751719 |  
                | Age: | postnatal day 5 |  
                |  |  
                |  |  
                | Specimen Label: | P5 |  
                | Detected: | true |  
                | Specimen Num: | 6 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:5751587 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2016-03-10 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1754428 |  
                |  |  
                | Stage: | TS28 |  
                | Assay Id: | MGI:5751719 |  
                | Age: | postnatal day 7 |  
                |  |  
                |  |  
                | Specimen Label: | P7 |  
                | Detected: | true |  
                | Specimen Num: | 7 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:5751587 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2016-03-11 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1754428 |  
                |  |  
                | Stage: | TS28 |  
                | Assay Id: | MGI:5751759 |  
                | Age: | postnatal week 8 |  
                |  |  
                |  |  
                | Specimen Label: | WT |  
                | Detected: | true |  
                | Specimen Num: | 1 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:5751587 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2016-03-11 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1754428 |  
                |  |  
                | Stage: | TS28 |  
                | Assay Id: | MGI:5751759 |  
                | Age: | postnatal week 8 |  
                |  |  
                |  |  
                | Specimen Label: | TLR2KO |  
                | Detected: | true |  
                | Specimen Num: | 2 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:5751601 |  
                | Assay Type: | Western blot |  
                | Annotation Date: | 2016-03-11 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1754423 |  
                |  |  
                | Stage: | TS23 |  
                | Assay Id: | MGI:5751774 |  
                | Age: | embryonic day 15.0 |  
                |  |  
                |  |  
                | Specimen Label: | TLR2+/+ |  
                | Detected: | true |  
                | Specimen Num: | 1 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:5751601 |  
                | Assay Type: | Western blot |  
                | Annotation Date: | 2016-03-11 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1754423 |  
                |  |  
                | Stage: | TS23 |  
                | Assay Id: | MGI:5751774 |  
                | Age: | embryonic day 15.0 |  
                |  |  
                |  |  
                | Specimen Label: | TLR2-/- |  
                | Detected: | true |  
                | Specimen Num: | 3 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:5751601 |  
                | Assay Type: | Western blot |  
                | Annotation Date: | 2016-03-11 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1754423 |  
                |  |  
                | Stage: | TS23 |  
                | Assay Id: | MGI:5751774 |  
                | Age: | embryonic day 15.0 |  
                |  |  
                |  |  
                | Specimen Label: | TLR2+/+ |  
                | Detected: | true |  
                | Specimen Num: | 2 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:5751601 |  
                | Assay Type: | Western blot |  
                | Annotation Date: | 2016-03-11 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1754423 |  
                |  |  
                | Stage: | TS23 |  
                | Assay Id: | MGI:5751774 |  
                | Age: | embryonic day 15.0 |  
                |  |  
                |  |  
                | Specimen Label: | TLR2-/- |  
                | Detected: | true |  
                | Specimen Num: | 4 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:7334814 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2022-09-07 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1689421 |  
                |  |  
                | Stage: | TS21 |  
                | Assay Id: | MGI:7334823 |  
                | Age: | embryonic day 13.0 |  
                | Image: | 1 |  
                |  |  
                | Specimen Label: | E13 |  
                | Detected: | true |  
                | Specimen Num: | 1 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:7334814 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2022-09-07 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1689422 |  
                |  |  
                | Stage: | TS22 |  
                | Assay Id: | MGI:7334823 |  
                | Age: | embryonic day 14.0 |  
                | Image: | 1 |  
                |  |  
                | Specimen Label: | E14 |  
                | Detected: | true |  
                | Specimen Num: | 2 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:7334814 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2022-09-07 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1689423 |  
                |  |  
                | Stage: | TS23 |  
                | Assay Id: | MGI:7334823 |  
                | Age: | embryonic day 15.0 |  
                | Image: | 1 |  
                |  |  
                | Specimen Label: | E15 |  
                | Detected: | true |  
                | Specimen Num: | 3 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:7334814 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2022-09-07 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1689424 |  
                |  |  
                | Stage: | TS24 |  
                | Assay Id: | MGI:7334823 |  
                | Age: | embryonic day 16.0 |  
                | Image: | 1 |  
                |  |  
                | Specimen Label: | E16 |  
                | Detected: | true |  
                | Specimen Num: | 4 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:7334814 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2022-09-07 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1689425 |  
                |  |  
                | Stage: | TS25 |  
                | Assay Id: | MGI:7334823 |  
                | Age: | embryonic day 17.0 |  
                | Image: | 1 |  
                |  |  
                | Specimen Label: | E17 |  
                | Detected: | true |  
                | Specimen Num: | 5 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:7334814 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2022-09-07 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1689426 |  
                |  |  
                | Stage: | TS26 |  
                | Assay Id: | MGI:7334823 |  
                | Age: | embryonic day 18.0 |  
                | Image: | 1 |  
                |  |  
                | Specimen Label: | E18 |  
                | Detected: | true |  
                | Specimen Num: | 6 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:7334814 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2022-09-07 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1689426 |  
                |  |  
                | Stage: | TS26 |  
                | Assay Id: | MGI:7334823 |  
                | Age: | embryonic day 19.0 |  
                | Image: | 1 |  
                |  |  
                | Specimen Label: | E19 |  
                | Detected: | true |  
                | Specimen Num: | 7 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:7334814 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2022-09-07 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1689427 |  
                |  |  
                | Stage: | TS27 |  
                | Assay Id: | MGI:7334823 |  
                | Age: | postnatal day 0 |  
                | Image: | 1 |  
                |  |  
                | Specimen Label: | P0 |  
                | Detected: | true |  
                | Specimen Num: | 8 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:7334814 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2022-09-07 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1689428 |  
                |  |  
                | Stage: | TS28 |  
                | Assay Id: | MGI:7334823 |  
                | Age: | postnatal day 4 |  
                | Image: | 1 |  
                |  |  
                | Specimen Label: | P4 |  
                | Detected: | true |  
                | Specimen Num: | 9 |  | • • • • • |