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Search results 1 to 100 out of 115 for Tprn

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0.079s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Taperin (TPRN) is a PP1 binding protein that is ancestrally related tophostensin. It localised prominently at the taper regions of hair cell stereocilia and has a role in sound perception []. Defects in human TPRN are the cause of deafness autosomal recessive type 79 (DFNB79). DFNB79 is characterised by progressive hearing loss leading to profound deafness. There are no symptoms of vestibular dysfunction [, ].
Publication
First Author: Rehman AU
Year: 2010
Journal: Am J Hum Genet
Title: Targeted capture and next-generation sequencing identifies C9orf75, encoding taperin, as the mutated gene in nonsyndromic deafness DFNB79.
Volume: 86
Issue: 3
Pages: 378-88
Publication
First Author: Qi J
Year: 2024
Journal: Mol Ther
Title: Critical role of TPRN rings in the stereocilia for hearing.
Volume: 32
Issue: 1
Pages: 204-217
Publication
First Author: Li Y
Year: 2010
Journal: Am J Hum Genet
Title: Mutations in TPRN cause a progressive form of autosomal-recessive nonsyndromic hearing loss.
Volume: 86
Issue: 3
Pages: 479-84
Publication
First Author: Men Y
Year: 2019
Journal: Front Med
Title: Tprn is essential for the integrity of stereociliary rootlet in cochlear hair cells in mice.
Volume: 13
Issue: 6
Pages: 690-704
Publication
First Author: Beausoleil SA
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Large-scale characterization of HeLa cell nuclear phosphoproteins.
Volume: 101
Issue: 33
Pages: 12130-5
Protein
Organism: Mus musculus/domesticus
Length: 749  
Fragment?: false
Publication
First Author: Chen M
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Progressive hearing loss and degeneration of hair cell stereocilia in taperin gene knockout mice.
Volume: 479
Issue: 4
Pages: 703-707
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692382
Age: postnatal adult
Image: JAX_1798512
Specimen Label: JAX_1798512
Detected: true
Specimen Num: 10
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692382
Age: postnatal adult
Image: JAX_1798509
Specimen Label: JAX_1798509
Specimen Num: 7
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692382
Age: postnatal adult
Image: JAX_1798520
Note: kidney
Specimen Label: JAX_1798520
Detected: true
Specimen Num: 18
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3267828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692382
Age: postnatal adult
Image: JAX_1798511
Specimen Label: JAX_1798511
Detected: true
Specimen Num: 9
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1898428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692382
Age: postnatal adult
Image: JAX_1798523
Specimen Label: JAX_1798523
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1672828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692382
Age: postnatal adult
Image: JAX_1798513
Specimen Label: JAX_1798513
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4428963
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:4823556
Age: embryonic day 14.5
Image: euxassay_015936_12
Specimen Label: euxassay_015936_12
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4428963
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:4823556
Age: embryonic day 14.5
Image: euxassay_015936_17
Specimen Label: euxassay_015936_17
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4428963
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:4823556
Age: embryonic day 14.5
Image: euxassay_015936_18
Specimen Label: euxassay_015936_18
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4428963
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:4823556
Age: embryonic day 14.5
Image: euxassay_015936_19
Specimen Label: euxassay_015936_19
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4428963
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:4823556
Age: embryonic day 14.5
Image: euxassay_015936_20
Specimen Label: euxassay_015936_20
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4428963
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:4823556
Age: embryonic day 14.5
Image: euxassay_015936_21
Specimen Label: euxassay_015936_21
Detected: true
Specimen Num: 6
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3276028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692382
Age: postnatal adult
Image: JAX_1798508
Specimen Label: JAX_1798508
Detected: true
Specimen Num: 6
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1685328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692382
Age: postnatal adult
Image: JAX_1798515
Specimen Label: JAX_1798515
Detected: true
Specimen Num: 13
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692382
Age: postnatal adult
Image: JAX_1798519
Specimen Label: JAX_1798519
Detected: true
Specimen Num: 17
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692382
Age: postnatal adult
Image: JAX_1798517
Specimen Label: JAX_1798517
Detected: true
Specimen Num: 15
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692382
Age: postnatal adult
Image: JAX_1798516
Specimen Label: JAX_1798516
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4428963
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823556
Age: embryonic day 14.5
Image: euxassay_015936_12
Specimen Label: euxassay_015936_12
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4428963
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823556
Age: embryonic day 14.5
Image: euxassay_015936_17
Specimen Label: euxassay_015936_17
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4428963
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823556
Age: embryonic day 14.5
Image: euxassay_015936_18
Specimen Label: euxassay_015936_18
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4428963
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823556
Age: embryonic day 14.5
Image: euxassay_015936_19
Specimen Label: euxassay_015936_19
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4428963
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823556
Age: embryonic day 14.5
Image: euxassay_015936_20
Specimen Label: euxassay_015936_20
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4428963
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823556
Age: embryonic day 14.5
Image: euxassay_015936_21
Specimen Label: euxassay_015936_21
Detected: true
Specimen Num: 6
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692382
Age: postnatal adult
Image: JAX_1798518
Specimen Label: JAX_1798518
Detected: true
Specimen Num: 16
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692382
Age: postnatal adult
Image: JAX_1798506
Specimen Label: JAX_1798506
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3273028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692382
Age: postnatal adult
Image: JAX_1798510
Specimen Label: JAX_1798510
Detected: true
Specimen Num: 8
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692382
Age: postnatal adult
Image: JAX_1798514
Specimen Label: JAX_1798514
Detected: true
Specimen Num: 12
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692382
Age: postnatal adult
Image: JAX_1798522
Specimen Label: JAX_1798522
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692382
Age: postnatal adult
Image: JAX_1798524
Specimen Label: JAX_1798524
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692382
Age: postnatal adult
Image: JAX_1798507
Specimen Label: JAX_1798507
Detected: true
Specimen Num: 5
Publication
First Author: Liu C
Year: 2018
Journal: Cell Rep
Title: GRXCR2 Regulates Taperin Localization Critical for Stereocilia Morphology and Hearing.
Volume: 25
Issue: 5
Pages: 1268-1280.e4
Publication    
First Author: Zhao B
Year: 2016
Journal: Elife
Title: Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function.
Volume: 5
Publication
First Author: Kazmierczak M
Year: 2017
Journal: J Neurosci
Title: Pejvakin, a Candidate Stereociliary Rootlet Protein, Regulates Hair Cell Function in a Cell-Autonomous Manner.
Volume: 37
Issue: 13
Pages: 3447-3464
Publication
First Author: Salles FT
Year: 2014
Journal: Cytoskeleton (Hoboken)
Title: CLIC5 stabilizes membrane-actin filament linkages at the base of hair cell stereocilia in a molecular complex with radixin, taperin, and myosin VI.
Volume: 71
Issue: 1
Pages: 61-78
Publication
First Author: Sundberg JP
Year: 2017
Journal: PLoS One
Title: Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
Volume: 12
Issue: 7
Pages: e0180682
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations