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Search results 1 to 100 out of 134 for Upf1

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0.05s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Drosophila melanogaster
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Hurt JA
Year: 2013
Journal: Genome Res
Title: Global analyses of UPF1 binding and function reveal expanded scope of nonsense-mediated mRNA decay.
Volume: 23
Issue: 10
Pages: 1636-50
Publication
First Author: Yaojia Cheng YX
Year: 2020
Journal: Int J Mol Med
Title: Aberrant expression of the UPF1 RNA surveillance gene disturbs keratinocyte homeostasis by stabilizing AREG.
Volume: 45
Issue: 4
Pages: 1163-1175
Publication
First Author: Medghalchi SM
Year: 2001
Journal: Hum Mol Genet
Title: Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability.
Volume: 10
Issue: 2
Pages: 99-105
MGI Directed Relationship Property
Name: Non-mouse_Gene_Symbol
Value: UPF1
Publication
First Author: Frischmeyer-Guerrerio PA
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Perturbation of thymocyte development in nonsense-mediated decay (NMD)-deficient mice.
Volume: 108
Issue: 26
Pages: 10638-43
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:2668019
Assay Type: Northern blot
Annotation Date: 2003-08-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:2668023
Age: embryonic day 7.0
Specimen Label: 7
Detected: true
Specimen Num: 1
GXD Expression        
Probe: MGI:2668019
Assay Type: Northern blot
Annotation Date: 2003-08-01
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:2668023
Age: embryonic day 11.0
Specimen Label: 11
Specimen Num: 2
GXD Expression        
Probe: MGI:2668019
Assay Type: Northern blot
Annotation Date: 2003-08-01
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:2668023
Age: embryonic day 15.0
Specimen Label: 15
Specimen Num: 3
GXD Expression        
Probe: MGI:2668019
Assay Type: Northern blot
Annotation Date: 2003-08-01
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:2668023
Age: embryonic day 17.0
Specimen Label: 17
Specimen Num: 4
GXD Expression    
Probe: MGI:6379271
Assay Type: RT-PCR
Annotation Date: 2019-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:6379286
Age: embryonic day 9.5
Image: S2
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6379271
Assay Type: RT-PCR
Annotation Date: 2019-12-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:6379286
Age: embryonic day 9.5
Image: S2
Specimen Label: HET
Detected: true
Specimen Num: 2
GXD Expression        
Probe: MGI:2668020
Assay Type: RT-PCR
Annotation Date: 2003-08-01
Strength: Not Specified
Sex: Female
Emaps: EMAPS:3526728
Stage: TS28
Assay Id: MGI:2668022
Age: postnatal adult
Specimen Label: Cumulus
Specimen Num: 3
GXD Expression      
Probe: MGI:2668020
Assay Type: RT-PCR
Annotation Date: 2003-08-01
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:2668022
Age: postnatal adult
Specimen Label: Oocyte
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5615981
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5615977
Age: embryonic day 14.5
Specimen Label: 1A ii/iii
Detected: true
Specimen Num: 1
Publication    
First Author: Selg M
Year: 2001
Journal: GenBank Submission
Title: Mus musculus nonsense mRNA reducing factor 1 NORF1 mRNA, complete cds
Pages: AF182947
Publication
First Author: Fanourgakis G
Year: 2016
Journal: PLoS Genet
Title: Chromatoid Body Protein TDRD6 Supports Long 3' UTR Triggered Nonsense Mediated mRNA Decay.
Volume: 12
Issue: 5
Pages: e1005857
Publication
First Author: Perlick HA
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Mammalian orthologues of a yeast regulator of nonsense transcript stability.
Volume: 93
Issue: 20
Pages: 10928-32
Publication
First Author: Banihashemi L
Year: 2006
Journal: Mol Cell Biol
Title: Upf1/Upf2 regulation of 3' untranslated region splice variants of AUF1 links nonsense-mediated and A+U-rich element-mediated mRNA decay.
Volume: 26
Issue: 23
Pages: 8743-54
Publication
First Author: Cho H
Year: 2012
Journal: Mol Cell
Title: Staufen1-mediated mRNA decay functions in adipogenesis.
Volume: 46
Issue: 4
Pages: 495-506
Publication
First Author: Hoefig KP
Year: 2013
Journal: Nat Struct Mol Biol
Title: Eri1 degrades the stem-loop of oligouridylated histone mRNAs to induce replication-dependent decay.
Volume: 20
Issue: 1
Pages: 73-81
Publication
First Author: Ciaudo C
Year: 2006
Journal: PLoS Genet
Title: Nuclear mRNA degradation pathway(s) are implicated in Xist regulation and X chromosome inactivation.
Volume: 2
Issue: 6
Pages: e94
Publication
First Author: Beauchamp MC
Year: 2019
Journal: PLoS One
Title: Loss of function mutation of Eftud2, the gene responsible for mandibulofacial dysostosis with microcephaly (MFDM), leads to pre-implantation arrest in mouse.
Volume: 14
Issue: 7
Pages: e0219280
Publication
First Author: Li T
Year: 2015
Journal: EMBO J
Title: Smg6/Est1 licenses embryonic stem cell differentiation via nonsense-mediated mRNA decay.
Volume: 34
Issue: 12
Pages: 1630-47
Publication
First Author: Rehfeld F
Year: 2018
Journal: Nat Commun
Title: The RNA-binding protein ARPP21 controls dendritic branching by functionally opposing the miRNA it hosts.
Volume: 9
Issue: 1
Pages: 1235
Publication
First Author: Kurosaki T
Year: 2021
Journal: Genome Biol
Title: NMD abnormalities during brain development in the Fmr1-knockout mouse model of fragile X syndrome.
Volume: 22
Issue: 1
Pages: 317
Publication
First Author: Clarke D
Year: 2001
Journal: Mamm Genome
Title: Comparative analysis of human 19p12-13 region in Fugu and mouse.
Volume: 12
Issue: 6
Pages: 478-83
Publication
First Author: Jolly LA
Year: 2013
Journal: Hum Mol Genet
Title: The UPF3B gene, implicated in intellectual disability, autism, ADHD and childhood onset schizophrenia regulates neural progenitor cell behaviour and neuronal outgrowth.
Volume: 22
Issue: 23
Pages: 4673-87
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication
First Author: Hosoda N
Year: 2005
Journal: Nat Struct Mol Biol
Title: CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells.
Volume: 12
Issue: 10
Pages: 893-901
Publication
First Author: Applequist SE
Year: 1997
Journal: Nucleic Acids Res
Title: Cloning and characterization of HUPF1, a human homolog of the Saccharomyces cerevisiae nonsense mRNA-reducing UPF1 protein.
Volume: 25
Issue: 4
Pages: 814-21
HT Experiment
Series Id: GSE63948
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Clerici M
Year: 2009
Journal: EMBO J
Title: Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2.
Volume: 28
Issue: 15
Pages: 2293-306
Publication
First Author: Chakrabarti S
Year: 2011
Journal: Mol Cell
Title: Molecular mechanisms for the RNA-dependent ATPase activity of Upf1 and its regulation by Upf2.
Volume: 41
Issue: 6
Pages: 693-703
Publication
First Author: Park E
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Staufen2 functions in Staufen1-mediated mRNA decay by binding to itself and its paralog and promoting UPF1 helicase but not ATPase activity.
Volume: 110
Issue: 2
Pages: 405-12
Allele    
Name: UPF1 regulator of nonsense transcripts homolog (yeast); wild type
Publication
First Author: Chamieh H
Year: 2008
Journal: Nat Struct Mol Biol
Title: NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity.
Volume: 15
Issue: 1
Pages: 85-93
Publication  
First Author: M Plank TD
Year: 2018
Journal: Bioessays
Title: RNA Decay Factor UPF1 Promotes Protein Decay: A Hidden Talent.
Volume: 40
Issue: 1
Publication    
First Author: Polaski JT
Year: 2021
Journal: Elife
Title: The origins and consequences of UPF1 variants in pancreatic adenosquamous carcinoma.
Volume: 10
Allele
Name: UPF1 regulator of nonsense transcripts homolog (yeast); targeted mutation 1, Harry C Dietz
Allele Type: Targeted
Attribute String: Null/knockout
Allele  
Name: UPF1 regulator of nonsense transcripts homolog (yeast); gene trap PST13395, Mammalian Functional Genomics Centre
Allele Type: Gene trapped
Allele  
Name: UPF1 regulator of nonsense transcripts homolog (yeast); gene trap XR0413, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
Allele  
Name: UPF1 regulator of nonsense transcripts homolog (yeast); gene trap F012A01, German Gene Trap Consortium
Allele Type: Gene trapped
Allele  
Name: UPF1 regulator of nonsense transcripts homolog (yeast); gene trap XN217, BayGenomics
Allele Type: Gene trapped
Allele  
Name: UPF1 regulator of nonsense transcripts homolog (yeast); gene trap PST4227, Mammalian Functional Genomics Centre
Allele Type: Gene trapped
Allele  
Name: UPF1 regulator of nonsense transcripts homolog (yeast); gene trap EUCE305d11, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
Allele  
Name: UPF1 regulator of nonsense transcripts homolog (yeast); gene trap EUCE0179h12, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
Allele  
Name: UPF1 regulator of nonsense transcripts homolog (yeast); gene trap EUCE0075b02, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
Interaction Experiment
Description: Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay.
Interaction Experiment
Description: Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay.
Genotype
Symbol: Upf1/Upf1
Background: involves: 129X1/SvJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Gregersen LH
Year: 2014
Journal: Mol Cell
Title: MOV10 Is a 5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs.
Volume: 54
Issue: 4
Pages: 573-85