Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
Not Specified |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
rabbit, European |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This family of plant proteins consists of WPP domain-associated proteins (WAPs). WAP interacts through its coiled-coil domain with several WPP-domain containing proteins and it is localized at the Golgi. It is required for complex formation of WPP-domain proteins []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Patel S |
Year: |
2005 |
Journal: |
Planta |
Title: |
The plant nuclear envelope protein MAF1 has an additional location at the Golgi and binds to a novel Golgi-associated coiled-coil protein. |
Volume: |
222 |
Issue: |
6 |
Pages: |
1028-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hennighausen L |
Year: |
1999 |
Journal: |
MGI Direct Data Submission |
Title: |
Mapping of the Wap gene to mouse Chromosome 11 |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Paleyanda RK |
Year: |
1994 |
Journal: |
Transgenic Res |
Title: |
Regulation of human protein C gene expression by the mouse WAP promoter. |
Volume: |
3 |
Issue: |
6 |
Pages: |
335-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Karlstetter M |
Year: |
2010 |
Journal: |
J Immunol |
Title: |
The novel activated microglia/macrophage WAP domain protein, AMWAP, acts as a counter-regulator of proinflammatory response. |
Volume: |
185 |
Issue: |
6 |
Pages: |
3379-90 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
81
|
Fragment?: |
false |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
85
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Hagiwara K |
Year: |
2003 |
Journal: |
J Immunol |
Title: |
Mouse SWAM1 and SWAM2 are antibacterial proteins composed of a single whey acidic protein motif. |
Volume: |
170 |
Issue: |
4 |
Pages: |
1973-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jalkanen J |
Year: |
2006 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Novel epididymal protease inhibitors with Kazal or WAP family domain. |
Volume: |
349 |
Issue: |
1 |
Pages: |
245-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hennighausen LG |
Year: |
1982 |
Journal: |
Nucleic Acids Res |
Title: |
Mouse whey acidic protein is a novel member of the family of 'four-disulfide core' proteins. |
Volume: |
10 |
Issue: |
8 |
Pages: |
2677-84 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Creamer BA |
Year: |
2009 |
Journal: |
Genesis |
Title: |
Longitudinal analysis of mammogenesis using a novel tetracycline-inducible mouse model and in vivo imaging. |
Volume: |
47 |
Issue: |
4 |
Pages: |
234-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schoenenberger CA |
Year: |
1988 |
Journal: |
EMBO J |
Title: |
Targeted c-myc gene expression in mammary glands of transgenic mice induces mammary tumours with constitutive milk protein gene transcription. |
Volume: |
7 |
Issue: |
1 |
Pages: |
169-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
McKnight RA |
Year: |
1996 |
Journal: |
Mol Reprod Dev |
Title: |
Severe position effects imposed on a 1 kb mouse whey acidic protein gene promoter are overcome by heterologous matrix attachment regions. |
Volume: |
44 |
Issue: |
2 |
Pages: |
179-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rival-Gervier S |
Year: |
2003 |
Journal: |
Biochim Biophys Acta |
Title: |
Pig whey acidic protein gene is surrounded by two ubiquitously expressed genes. |
Volume: |
1627 |
Issue: |
1 |
Pages: |
7-14 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
174
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Sympson CJ |
Year: |
1994 |
Journal: |
J Cell Biol |
Title: |
Targeted expression of stromelysin-1 in mammary gland provides evidence for a role of proteinases in branching morphogenesis and the requirement for an intact basement membrane for tissue-specific gene expression. |
Volume: |
125 |
Issue: |
3 |
Pages: |
681-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hagiwara K |
Year: |
2002 |
Journal: |
GenBank Submission |
Title: |
Mus musculus single WAP motif protein 1 mRNA, complete cds |
|
|
Pages: |
AF276974 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hagiwara K |
Year: |
2002 |
Journal: |
GenBank Submission |
Title: |
Mus musculus single WAP motif protein 2 mRNA, complete cds |
|
|
Pages: |
AF276975 |
|
•
•
•
•
•
|
Publication |
First Author: |
Campbell SM |
Year: |
1984 |
Journal: |
Nucleic Acids Res |
Title: |
Comparison of the whey acidic protein genes of the rat and mouse. |
Volume: |
12 |
Issue: |
22 |
Pages: |
8685-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Triplett AA |
Year: |
2005 |
Journal: |
Genesis |
Title: |
Expression of the whey acidic protein (Wap) is necessary for adequate nourishment of the offspring but not functional differentiation of mammary epithelial cells. |
Volume: |
43 |
Issue: |
1 |
Pages: |
1-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rival S |
Year: |
2001 |
Journal: |
Gene |
Title: |
Cloning, transcription and chromosomal localization of the porcine whey acidic protein gene and its expression in HC11 cell line. |
Volume: |
267 |
Issue: |
1 |
Pages: |
37-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hennighausen L |
Year: |
1994 |
Journal: |
Cell Growth Differ |
Title: |
Whey acidic protein extrinsically expressed from the mouse mammary tumor virus long terminal repeat results in hyperplasia of the coagulation gland epithelium and impaired mammary development. |
Volume: |
5 |
Issue: |
6 |
Pages: |
607-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin CQ |
Year: |
1995 |
Journal: |
J Cell Biol |
Title: |
Extracellular matrix regulates whey acidic protein gene expression by suppression of TGF-alpha in mouse mammary epithelial cells: studies in culture and in transgenic mice. |
Volume: |
129 |
Issue: |
4 |
Pages: |
1115-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wen J |
Year: |
1995 |
Journal: |
Mol Reprod Dev |
Title: |
Expression of whey acidic protein (WAP) genes in tissues other than the mammary gland in normal and transgenic mice expressing mWAP/hGH fusion gene. |
Volume: |
41 |
Issue: |
4 |
Pages: |
399-406 |
|
•
•
•
•
•
|
Publication |
First Author: |
Santarelli R |
Year: |
1996 |
Journal: |
Oncogene |
Title: |
SV40 T-antigen induces breast cancer formation with a high efficiency in lactating and virgin WAP-SV-T transgenic animals but with a low efficiency in ovariectomized animals. |
Volume: |
12 |
Issue: |
3 |
Pages: |
495-505 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rucker EB |
Year: |
1997 |
Journal: |
Mol Reprod Dev |
Title: |
Cre-mediated recombination at the murine whey acidic protein (mWAP) locus. |
Volume: |
48 |
Issue: |
3 |
Pages: |
324-31 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
180
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
124
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Kannius-Janson M |
Year: |
1998 |
Journal: |
Biochem J |
Title: |
Studies of the regulation of the mouse carboxyl ester lipase gene in mammary gland. |
Volume: |
336 ( Pt 3) |
|
Pages: |
577-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Asselin-Labat ML |
Year: |
2007 |
Journal: |
Nat Cell Biol |
Title: |
Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation. |
Volume: |
9 |
Issue: |
2 |
Pages: |
201-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Seagroves TN |
Year: |
2010 |
Journal: |
Am J Pathol |
Title: |
VHL deletion impairs mammary alveologenesis but is not sufficient for mammary tumorigenesis. |
Volume: |
176 |
Issue: |
5 |
Pages: |
2269-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shin HY |
Year: |
2016 |
Journal: |
Nat Genet |
Title: |
Hierarchy within the mammary STAT5-driven Wap super-enhancer. |
Volume: |
48 |
Issue: |
8 |
Pages: |
904-911 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Piletz JE |
Year: |
1981 |
Journal: |
J Biol Chem |
Title: |
Biochemical characterization of a novel whey protein from murine milk. |
Volume: |
256 |
Issue: |
22 |
Pages: |
11509-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Creamer BA |
Year: |
2010 |
Journal: |
Mol Cell Biol |
Title: |
Stat5 promotes survival of mammary epithelial cells through transcriptional activation of a distinct promoter in Akt1. |
Volume: |
30 |
Issue: |
12 |
Pages: |
2957-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Reczek CR |
Year: |
2016 |
Journal: |
Oncotarget |
Title: |
The DNA resection protein CtIP promotes mammary tumorigenesis. |
Volume: |
7 |
Issue: |
22 |
Pages: |
32172-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schmidt JW |
Year: |
2014 |
Journal: |
Mol Cell Biol |
Title: |
Stat5 regulates the phosphatidylinositol 3-kinase/Akt1 pathway during mammary gland development and tumorigenesis. |
Volume: |
34 |
Issue: |
7 |
Pages: |
1363-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shakya R |
Year: |
2011 |
Journal: |
Science |
Title: |
BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity. |
Volume: |
334 |
Issue: |
6055 |
Pages: |
525-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shakya R |
Year: |
2008 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
The basal-like mammary carcinomas induced by Brca1 or Bard1 inactivation implicate the BRCA1/BARD1 heterodimer in tumor suppression. |
Volume: |
105 |
Issue: |
19 |
Pages: |
7040-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Oliver CH |
Year: |
2012 |
Journal: |
Genes Dev |
Title: |
The Stat6-regulated KRAB domain zinc finger protein Zfp157 regulates the balance of lineages in mammary glands and compensates for loss of Gata-3. |
Volume: |
26 |
Issue: |
10 |
Pages: |
1086-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Klinakis A |
Year: |
2009 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Igf1r as a therapeutic target in a mouse model of basal-like breast cancer. |
Volume: |
106 |
Issue: |
7 |
Pages: |
2359-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stellas D |
Year: |
2014 |
Journal: |
J Natl Cancer Inst |
Title: |
Therapeutic effects of an anti-Myc drug on mouse pancreatic cancer. |
Volume: |
106 |
Issue: |
12 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Stratikopoulos EE |
Year: |
2015 |
Journal: |
Cancer Cell |
Title: |
Kinase and BET Inhibitors Together Clamp Inhibition of PI3K Signaling and Overcome Resistance to Therapy. |
Volume: |
27 |
Issue: |
6 |
Pages: |
837-51 |
|
•
•
•
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Publication |
First Author: |
Stratikopoulos EE |
Year: |
2019 |
Journal: |
Oncogene |
Title: |
Mouse ER+/PIK3CAH1047R breast cancers caused by exogenous estrogen are heterogeneously dependent on estrogen and undergo BIM-dependent apoptosis with BH3 and PI3K agents. |
Volume: |
38 |
Issue: |
1 |
Pages: |
47-59 |
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Publication |
First Author: |
Elias S |
Year: |
2014 |
Journal: |
Stem Cell Reports |
Title: |
Huntingtin regulates mammary stem cell division and differentiation. |
Volume: |
2 |
Issue: |
4 |
Pages: |
491-506 |
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Publication |
First Author: |
Ludwig T |
Year: |
2001 |
Journal: |
Oncogene |
Title: |
Development of mammary adenocarcinomas by tissue-specific knockout of Brca2 in mice. |
Volume: |
20 |
Issue: |
30 |
Pages: |
3937-48 |
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