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Search results 1 to 100 out of 151 for Xirp2

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Hits by Category

Type Details Score
Gene
129446 | XIRP2
Type: gene
Organism: human
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Gene
708348 | XIRP2
Type: gene
Organism: macaque, rhesus
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Gene
100488785 | xirp2
Type: gene
Organism: frog, western clawed
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Gene
311098 | Xirp2
Type: gene
Organism: rat
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Gene
478778 | XIRP2
Type: gene
Organism: dog, domestic
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Gene
459707 | XIRP2
Type: gene
Organism: chimpanzee
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Gene
506090 | XIRP2
Type: gene
Organism: cattle
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Gene
772075 | XIRP2
Type: gene
Organism: chicken
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Protein Coding Gene
MGI:2685198 | Xirp2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR030107 | XIRP2
Type: Family
Description: Proteins in this family contains Xin repeats, which define anactin-binding motif. In humans two Xin-repeat proteins have been identified, XIRP1 and XIRP2. They are expressed during early developmental stages of cardiac and skeletal muscles []and have an important role in cardiac development and function []. They bind to and stabilise F-actin [].This entry represents XIRP2, also known as Xin-beta. In mouse, it initiates the maturation of the intercalated discs (ICDs)during postnatal heart development [].
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Publication
23261932 | J:193412
First Author: Wang Q
Year: 2013
Journal: Dev Biol
Title: The Xin repeat-containing protein, mXinβ, initiates the maturation of the intercalated discs during postnatal heart development.
Volume: 374
Issue: 2
Pages: 264-80
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Gene
100874011 | XIRP2-AS1
Type: gene
Organism: human
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Publication
37294664 | J:338149
   
First Author: Wagner EL
Year: 2023
Journal: Elife
Title: Repair of noise-induced damage to stereocilia F-actin cores is facilitated by XIRP2 and its novel mechanosensor domain.
Volume: 12
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Protein
Q4U4S6
Organism: Mus musculus/domesticus
Length: 3784  
Fragment?: false
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Protein
B2BBR6
Organism: Mus musculus/domesticus
Length: 701  
Fragment?: false
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Protein
A9YSG0
Organism: Mus musculus/domesticus
Length: 101  
Fragment?: true
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Protein
A9YSG1
Organism: Mus musculus/domesticus
Length: 374  
Fragment?: true
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Protein
B2BBR8
Organism: Mus musculus/domesticus
Length: 811  
Fragment?: false
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Protein
A0A5F8MQC2
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: true
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Protein
A0A5F8MPJ5
Organism: Mus musculus/domesticus
Length: 930  
Fragment?: false
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Protein
A0A5F8MP54
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: true
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Protein
A9YSG2
Organism: Mus musculus/domesticus
Length: 118  
Fragment?: true
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Protein
A0A089VPF9
Organism: Mus musculus/domesticus
Length: 931  
Fragment?: false
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Protein
A9YSG3
Organism: Mus musculus/domesticus
Length: 67  
Fragment?: true
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Protein
B2BBR7
Organism: Mus musculus/domesticus
Length: 795  
Fragment?: false
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Protein
A0A5F8MPR4
Organism: Mus musculus/domesticus
Length: 3512  
Fragment?: false
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Protein
B2BBR9
Organism: Mus musculus/domesticus
Length: 820  
Fragment?: false
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Publication
16631741 | -
First Author: van der Ven PF
Year: 2006
Journal: Exp Cell Res
Title: Unusual splicing events result in distinct Xin isoforms that associate differentially with filamin c and Mena/VASP.
Volume: 312
Issue: 11
Pages: 2154-67
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Publication
15454575 | -
First Author: Pacholsky D
Year: 2004
Journal: J Cell Sci
Title: Xin repeats define a novel actin-binding motif.
Volume: 117
Issue: Pt 22
Pages: 5257-68
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Publication
24725425 | -
 
First Author: Wang Q
Year: 2014
Journal: Int Rev Cell Mol Biol
Title: New insights into the roles of Xin repeat-containing proteins in cardiac development, function, and disease.
Volume: 310
Pages: 89-128
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Publication
25772365 | J:228182
First Author: Scheffer DI
Year: 2015
Journal: Cell Rep
Title: XIRP2, an actin-binding protein essential for inner ear hair-cell stereocilia.
Volume: 10
Issue: 11
Pages: 1811-8
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Publication
25653358 | J:219773
First Author: Francis SP
Year: 2015
Journal: J Neurosci
Title: A short splice form of Xin-actin binding repeat containing 2 (XIRP2) lacking the Xin repeats is required for maintenance of stereocilia morphology and hearing function.
Volume: 35
Issue: 5
Pages: 1999-2014
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Publication
20093629 | J:170869
First Author: McCalmon SA
Year: 2010
Journal: Circ Res
Title: Modulation of angiotensin II-mediated cardiac remodeling by the MEF2A target gene Xirp2.
Volume: 106
Issue: 5
Pages: 952-60
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Publication
27206985 | J:237309
First Author: Leber Y
Year: 2016
Journal: Hum Mol Genet
Title: Filamin C is a highly dynamic protein associated with fast repair of myofibrillar microdamage.
Volume: 25
Issue: 13
Pages: 2776-2788
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Publication
29306897 | J:255706
 
First Author: Huang L
Year: 2018
Journal: J Am Heart Assoc
Title: Critical Roles of Xirp Proteins in Cardiac Conduction and Their Rare Variants Identified in Sudden Unexplained Nocturnal Death Syndrome and Brugada Syndrome in Chinese Han Population.
Volume: 7
Issue: 1
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Publication
30410445 | J:307828
 
First Author: Farrell E
Year: 2018
Journal: Front Physiol
Title: Transcriptome Analysis of Cardiac Hypertrophic Growth in MYBPC3-Null Mice Suggests Early Responders in Hypertrophic Remodeling.
Volume: 9
Pages: 1442
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Protein Coding Gene
MGP_CAROLIEiJ_G0023610 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0025788 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0025765 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0025734 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0025760 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0025520 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2685198 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026207 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0024984 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0025500 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0025631 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0025594 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0025720 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0025623 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0026264 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0024725 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0025052 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0025061 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0024532 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
32938943 | J:296931
First Author: Guo H
Year: 2020
Journal: Nat Commun
Title: Intercalated disc protein Xinβ is required for Hippo-YAP signaling in the heart.
Volume: 11
Issue: 1
Pages: 4666
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Publication
20360251 | J:158491
First Author: Wang Q
Year: 2010
Journal: Circ Res
Title: Essential roles of an intercalated disc protein, mXinbeta, in postnatal heart growth and survival.
Volume: 106
Issue: 9
Pages: 1468-78
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GXD Expression
GXD Expression
     
Probe: MGI:5691551
Assay Type: Northern blot
Annotation Date: 2015-10-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5691552
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5691551
Assay Type: Northern blot
Annotation Date: 2015-10-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5691552
Age: postnatal adult
Specimen Label: Brain
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5691551
Assay Type: Northern blot
Annotation Date: 2015-10-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5691552
Age: postnatal adult
Specimen Label: Spleen
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5691551
Assay Type: Northern blot
Annotation Date: 2015-10-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5691552
Age: postnatal adult
Specimen Label: Lung
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:5691551
Assay Type: Northern blot
Annotation Date: 2015-10-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5691552
Age: postnatal adult
Specimen Label: Liver
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:5691551
Assay Type: Northern blot
Annotation Date: 2015-10-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:5691552
Age: postnatal adult
Specimen Label: Skeletal muscle
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:5691551
Assay Type: Northern blot
Annotation Date: 2015-10-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5691552
Age: postnatal adult
Specimen Label: Kidney
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:5691551
Assay Type: Northern blot
Annotation Date: 2015-10-15
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5691552
Age: postnatal adult
Specimen Label: Testis
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:7407303
Assay Type: RT-PCR
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619427
Stage: TS27
Assay Id: MGI:7407314
Age: postnatal day 3
Image: 2
Specimen Label: Full-length Ear
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7407303
Assay Type: RT-PCR
Annotation Date: 2022-12-13
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7407314
Age: postnatal day 3
Image: 2
Specimen Label: Full-length Heart
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7407304
Assay Type: RT-PCR
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619427
Stage: TS27
Assay Id: MGI:7407316
Age: postnatal day 3
Image: 2
Specimen Label: Gm1322 Ear
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:7407304
Assay Type: RT-PCR
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7407316
Age: postnatal day 3
Image: 2
Specimen Label: Gm1322 Heart
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:7407305
Assay Type: RT-PCR
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619427
Stage: TS27
Assay Id: MGI:7407317
Age: postnatal day 3
Image: 2
Specimen Label: Exons 6/7 Ear
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:7407305
Assay Type: RT-PCR
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7407317
Age: postnatal day 3
Image: 2
Specimen Label: Exons 6/7 Heart
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:7407308
Assay Type: RT-PCR
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619427
Stage: TS27
Assay Id: MGI:7407318
Age: postnatal day 3
Image: 2
Specimen Label: Exons 6/9 Ear
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:7407308
Assay Type: RT-PCR
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7407318
Age: postnatal day 3
Image: 2
Specimen Label: Exons 6/9 Heart
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:7407322
Assay Type: Western blot
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Stage: TS28
Assay Id: MGI:7407324
Age: postnatal
Image: 2
Specimen Label: Hair bundles
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7407323
Assay Type: Western blot
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Stage: TS28
Assay Id: MGI:7407325
Age: postnatal
Image: 9
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7407322
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7407328
Age: postnatal day 4
Image: 9A -exon 6 WT utricle
Note: Expression in vestibular hair bundles.
Specimen Label: 9A -exon 6 WT utricle
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7407323
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7407327
Age: postnatal day 4
Image: 9A D-18 WT utricle
Note: Expression in vestibular hair bundles.
Specimen Label: 9A D-18 WT utricle
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
Probe: MGI:7407323
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729326
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7407327
Age: embryonic day 18.0
Image: 3B E18
Note: Onset of expression at E18, specifically in apical regions of hair cells and stereocilia.
Specimen Label: 3B E18
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:7407323
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7407327
Age: postnatal day 4
Image: 3B P4
Note: Expression specifically in apical regions of hair cells and stereocilia.
Specimen Label: 3B P4
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:7407323
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7407327
Age: postnatal day 30
Image: 3B P30
Note: Expression is heterogeneous: strong expression in some stereocilia with weaker expression in stereocilia in same bundle.
Specimen Label: 3B P30
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:7407323
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7407327
Age: postnatal day 4
Image: 3C
Note: Expression in vestibular hair bundle.
Specimen Label: 3C
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:7407323
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729326
Pattern: Widespread
Stage: TS26
Assay Id: MGI:7407327
Age: embryonic day 18.0
Image: 8E WT
Note: Expression in all vestibular hair cells.
Specimen Label: 8E WT
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
Probe: MGI:7407322
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7407328
Age: postnatal day 4
Image: 9A -exon 6 WT cochlea
Note: Expression in cochlear hair bundles.
Specimen Label: 9A -exon 6 WT cochlea
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7407323
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7407327
Age: postnatal day 4
Image: 9A D-18 WT cochlea
Note: Expression in cochlear hair bundles.
Specimen Label: 9A D-18 WT cochlea
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
   
Probe: MGI:7407323
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-13
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1759723
Stage: TS23
Assay Id: MGI:7407327
Age: embryonic day 15.0
Image: 3A E15
Specimen Label: 3A E15
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7407323
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759726
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7407327
Age: embryonic day 18.0
Image: 3A E18
Note: Onset of expression in hair cells beginning at E18, coinciding with emergence of hair bundle.
Specimen Label: 3A E18
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7407323
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7407327
Age: postnatal day 4
Image: 3A P4
Note: Expression localized to apical region of hair cell and bundle.
Specimen Label: 3A P4
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:7407323
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7407327
Age: postnatal day 10
Image: 3A P10
Note: Expression localized to apical region of hair cell and bundle.
Specimen Label: 3A P10
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:7407323
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7407327
Age: postnatal day 20
Image: 3A P20
Note: Expression localized to apical region of hair cell and bundle.
Specimen Label: 3A P20
Detected: true
Specimen Num: 5
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Publication
16708114 | J:112201
First Author: Jung-Ching Lin J
Year: 2005
Journal: J Med Sci
Title: Structure, Expression, and Function of a Novel Intercalated Disc Protein, Xin.
Volume: 25
Issue: 5
Pages: 215-222
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Publication
18682726 | J:140126
First Author: Grosskurth SE
Year: 2008
Journal: PLoS One
Title: Emergence of Xin demarcates a key innovation in heart evolution.
Volume: 3
Issue: 8
Pages: e2857
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Publication
17046827 | J:117604
First Author: Huang HT
Year: 2006
Journal: J Biol Chem
Title: Myomaxin is a novel transcriptional target of MEF2A that encodes a Xin-related alpha-actinin-interacting protein.
Volume: 281
Issue: 51
Pages: 39370-9
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Publication
17766470 | J:132079
First Author: Gustafson-Wagner EA
Year: 2007
Journal: Am J Physiol Heart Circ Physiol
Title: Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects.
Volume: 293
Issue: 5
Pages: H2680-92
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Publication
18327258 | J:133725
First Author: Tran PV
Year: 2008
Journal: Nat Genet
Title: THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia.
Volume: 40
Issue: 4
Pages: 403-410
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Publication
21689717 | J:175560
First Author: Lamberti A
Year: 2011
Journal: Biochimie
Title: Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.
Volume: 93
Issue: 10
Pages: 1738-46
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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