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Search results 1 to 100 out of 242 for Zp2

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: cat, domestic
Gene
Type: gene
Organism: pig, domestic
Gene
Type: gene
Organism: rabbit, European
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression  
Probe: MGI:6468327
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-23
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6468575
Age: postnatal week 23
Image: 1H Zp2 Control
Specimen Label: 1H Zp2 Control
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6468327
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-23
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6468575
Age: postnatal week 23
Image: 1H Zp2 cKO
Note: Oogenesis in the mutant is comparable to that seen in controls.
Specimen Label: 1H Zp2 cKO
Detected: true
Specimen Num: 2
Publication
First Author: Liu W
Year: 2017
Journal: Hum Genet
Title: Dosage effects of ZP2 and ZP3 heterozygous mutations cause human infertility.
Volume: 136
Issue: 8
Pages: 975-985
Publication
First Author: Liu SL
Year: 2023
Journal: iScience
Title: A heterozygous ZP2 mutation causes zona pellucida defects and female infertility in mouse and human.
Volume: 26
Issue: 10
Pages: 107828
Publication
First Author: Burkart AD
Year: 2012
Journal: J Cell Biol
Title: Ovastacin, a cortical granule protease, cleaves ZP2 in the zona pellucida to prevent polyspermy.
Volume: 197
Issue: 1
Pages: 37-44
Publication
First Author: Avella MA
Year: 2014
Journal: J Cell Biol
Title: A single domain of the ZP2 zona pellucida protein mediates gamete recognition in mice and humans.
Volume: 205
Issue: 6
Pages: 801-9
Publication
First Author: Tokuhiro K
Year: 2018
Journal: Dev Cell
Title: Glycan-Independent Gamete Recognition Triggers Egg Zinc Sparks and ZP2 Cleavage to Prevent Polyspermy.
Volume: 46
Issue: 5
Pages: 627-640.e5
Publication
First Author: Hoodbhoy T
Year: 2006
Journal: Mol Cell Biol
Title: ZP2 and ZP3 traffic independently within oocytes prior to assembly into the extracellular zona pellucida.
Volume: 26
Issue: 21
Pages: 7991-8
Publication
First Author: Jimenez-Movilla M
Year: 2011
Journal: J Cell Sci
Title: ZP2 and ZP3 cytoplasmic tails prevent premature interactions and ensure incorporation into the zona pellucida.
Volume: 124
Issue: Pt 6
Pages: 940-50
Publication
First Author: Howes E
Year: 2001
Journal: J Cell Sci
Title: Interactions between mouse ZP2 glycoprotein and proacrosin; a mechanism for secondary binding of sperm to the zona pellucida during fertilization.
Volume: 114
Issue: Pt 22
Pages: 4127-36
Publication
First Author: Rankin TL
Year: 2003
Journal: Dev Cell
Title: Fertility and taxon-specific sperm binding persist after replacement of mouse sperm receptors with human homologs.
Volume: 5
Issue: 1
Pages: 33-43
Publication
First Author: Gahlay G
Year: 2010
Journal: Science
Title: Gamete recognition in mice depends on the cleavage status of an egg's zona pellucida protein.
Volume: 329
Issue: 5988
Pages: 216-9
Publication
First Author: Liang LF
Year: 1990
Journal: Mol Cell Biol
Title: Oocyte-specific expression of mouse Zp-2: developmental regulation of the zona pellucida genes.
Volume: 10
Issue: 4
Pages: 1507-15
Publication
First Author: Rankin TL
Year: 2001
Journal: Development
Title: Defective zonae pellucidae in Zp2-null mice disrupt folliculogenesis, fertility and development.
Volume: 128
Issue: 7
Pages: 1119-26
Publication
First Author: Vaccaro MC
Year: 2001
Journal: Mol Reprod Dev
Title: Primary structure and developmental expression of Dp ZP2, a vitelline envelope glycoprotein homolog of mouse ZP2, in Discoglossus pictus, one of the oldest living Anuran species.
Volume: 59
Issue: 2
Pages: 133-43
Publication
First Author: Liang LF
Year: 1993
Journal: Dev Biol
Title: Conservation of mammalian secondary sperm receptor genes enables the promoter of the human gene to function in mouse oocytes.
Volume: 156
Issue: 2
Pages: 399-408
Publication
First Author: Tong ZB
Year: 1995
Journal: J Biol Chem
Title: Inhibition of zona pellucida gene expression by antisense oligonucleotides injected into mouse oocytes.
Volume: 270
Issue: 2
Pages: 849-53
Publication
First Author: Epifano O
Year: 1995
Journal: Development
Title: Coordinate expression of the three zona pellucida genes during mouse oogenesis.
Volume: 121
Issue: 7
Pages: 1947-56
Publication
First Author: Prasad SV
Year: 2000
Journal: Cells Tissues Organs
Title: Structure and function of the proteins of the mammalian Zona pellucida.
Volume: 166
Issue: 2
Pages: 148-64
Publication
First Author: Soyal SM
Year: 2000
Journal: Development
Title: FIGalpha, a germ cell-specific transcription factor required for ovarian follicle formation.
Volume: 127
Issue: 21
Pages: 4645-54
Publication  
First Author: Naz RK
Year: 2005
Journal: Front Biosci
Title: Gene knockouts that cause female infertility: search for novel contraceptive targets.
Volume: 10
Pages: 2447-59
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Voyle RB
Year: 1999
Journal: Zygote
Title: Isolation and characterisation of zona pellucida A (ZPA) cDNAs from two species of marsupial: regulated oocyte-specific expression of ZPA transcripts.
Volume: 7
Issue: 3
Pages: 239-48
Publication
First Author: Millar SE
Year: 1993
Journal: Dev Biol
Title: ZAP-1 DNA binding activity is first detected at the onset of zona pellucida gene expression in embryonic mouse oocytes.
Volume: 158
Issue: 2
Pages: 410-3
GXD Expression    
Probe: MGI:2655175
Assay Type: RT-PCR
Annotation Date: 2003-04-22
Strength: Absent
Sex: Female
Emaps: EMAPS:1796520
Stage: TS20
Assay Id: MGI:2655181
Age: embryonic day 12.5
Image: 1
Specimen Label: 100 13 dpc oogonia
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:2655175
Assay Type: RT-PCR
Annotation Date: 2003-04-22
Strength: Present
Sex: Female
Emaps: EMAPS:1796523
Stage: TS23
Assay Id: MGI:2655181
Age: embryonic day 15.5
Image: 1
Specimen Label: 100 16 dpc oocytes
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:2655175
Assay Type: RT-PCR
Annotation Date: 2003-04-22
Strength: Present
Sex: Female
Emaps: EMAPS:1796526
Stage: TS26
Assay Id: MGI:2655181
Age: embryonic day 18.5
Image: 1
Specimen Label: 100 19 dpc oocytes
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:2655175
Assay Type: RT-PCR
Annotation Date: 2003-04-22
Strength: Present
Sex: Female
Emaps: EMAPS:3102527
Stage: TS27
Assay Id: MGI:2655181
Age: postnatal newborn
Image: 1
Specimen Label: 100 newborn oocytes
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:2655175
Assay Type: RT-PCR
Annotation Date: 2003-04-22
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:2655181
Age: postnatal day 10
Image: 1
Specimen Label: 0.0001 10 day oocytes
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:2655175
Assay Type: RT-PCR
Annotation Date: 2003-04-22
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:2655181
Age: postnatal day 10
Image: 1
Specimen Label: 0.001 10 day oocyte
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:2655175
Assay Type: RT-PCR
Annotation Date: 2003-04-22
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:2655181
Age: postnatal day 10
Image: 1
Specimen Label: 0.01 10 day oocyte
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:2655175
Assay Type: RT-PCR
Annotation Date: 2003-04-22
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:2655181
Age: postnatal day 10
Image: 1
Specimen Label: 0.1 10 day oocyte
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:2655175
Assay Type: RT-PCR
Annotation Date: 2003-04-22
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:2655181
Age: postnatal day 10
Image: 1
Specimen Label: 1 10 day oocyte
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:2655175
Assay Type: RT-PCR
Annotation Date: 2006-05-25
Strength: Present
Sex: Female
Emaps: EMAPS:1796526
Stage: TS26
Assay Id: MGI:3623260
Age: embryonic day 19.0
Image: 2
Specimen Label: Single 19.5 dpc oocyte
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:2655175
Assay Type: RT-PCR
Annotation Date: 2006-05-25
Strength: Present
Sex: Female
Emaps: EMAPS:1796526
Stage: TS26
Assay Id: MGI:3623260
Age: embryonic day 19.0
Image: 2
Specimen Label: Single 19.5 dpc oocyte
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:2655175
Assay Type: RT-PCR
Annotation Date: 2006-05-25
Strength: Present
Sex: Female
Emaps: EMAPS:1796526
Stage: TS26
Assay Id: MGI:3623260
Age: embryonic day 19.0
Image: 2
Specimen Label: Single 19.5 dpc oocyte
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:2655175
Assay Type: RT-PCR
Annotation Date: 2006-05-25
Strength: Present
Sex: Female
Emaps: EMAPS:1796526
Stage: TS26
Assay Id: MGI:3623260
Age: embryonic day 19.0
Image: 2
Specimen Label: Single 19.5 dpc oocyte
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:2655175
Assay Type: RT-PCR
Annotation Date: 2006-05-25
Strength: Present
Sex: Female
Emaps: EMAPS:1796526
Stage: TS26
Assay Id: MGI:3623260
Age: embryonic day 19.0
Image: 2
Specimen Label: Single 19.5 dpc oocyte
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:2655175
Assay Type: RT-PCR
Annotation Date: 2006-05-25
Strength: Present
Sex: Female
Emaps: EMAPS:1796526
Stage: TS26
Assay Id: MGI:3623260
Age: embryonic day 19.0
Image: 2
Specimen Label: Single 19.5 dpc oocyte
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:2655175
Assay Type: RT-PCR
Annotation Date: 2006-05-25
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:3623260
Age: postnatal day 10
Image: 2
Specimen Label: 10 day oocyte
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:3839393
Assay Type: RT-PCR
Annotation Date: 2009-04-10
Strength: Present
Sex: Female
Emaps: EMAPS:1796227
Stage: TS27
Assay Id: MGI:3839600
Age: postnatal day 0
Image: 4
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3839393
Assay Type: RT-PCR
Annotation Date: 2009-04-10
Strength: Present
Sex: Female
Emaps: EMAPS:1796227
Stage: TS27
Assay Id: MGI:3839600
Age: postnatal day 0
Image: 4
Specimen Label: -/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5637970
Assay Type: RT-PCR
Annotation Date: 2015-06-01
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5637984
Age: postnatal day 4
Specimen Label: testis1
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5637970
Assay Type: RT-PCR
Annotation Date: 2015-06-01
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5637984
Age: postnatal day 4
Specimen Label: testis2
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5637970
Assay Type: RT-PCR
Annotation Date: 2015-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:5637984
Age: postnatal day 4
Specimen Label: ovary
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5637970
Assay Type: RT-PCR
Annotation Date: 2015-06-01
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5637984
Age: postnatal day 4
Specimen Label: testis1
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5637970
Assay Type: RT-PCR
Annotation Date: 2015-06-01
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5637984
Age: postnatal day 4
Specimen Label: testis2
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5637970
Assay Type: RT-PCR
Annotation Date: 2015-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:5637984
Age: postnatal day 4
Specimen Label: ovary
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5637970
Assay Type: RT-PCR
Annotation Date: 2015-06-01
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5637984
Age: postnatal day 13
Specimen Label: testis1
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5637970
Assay Type: RT-PCR
Annotation Date: 2015-06-01
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5637984
Age: postnatal day 13
Specimen Label: testis2
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:5637970
Assay Type: RT-PCR
Annotation Date: 2015-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:5637984
Age: postnatal day 13
Specimen Label: ovary
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:5637970
Assay Type: RT-PCR
Annotation Date: 2015-06-01
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5637984
Age: postnatal day 13
Specimen Label: testis1
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:5637970
Assay Type: RT-PCR
Annotation Date: 2015-06-01
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5637984
Age: postnatal day 13
Specimen Label: testis2
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:5637970
Assay Type: RT-PCR
Annotation Date: 2015-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:5637984
Age: postnatal day 13
Specimen Label: ovary
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:2655175
Assay Type: RT-PCR
Annotation Date: 2006-05-25
Strength: Absent
Sex: Female
Emaps: EMAPS:3562728
Stage: TS28
Assay Id: MGI:3623260
Age: postnatal day 10
Image: 2
Specimen Label: Follicle cell (100)
Detected: false
Specimen Num: 8
GXD Expression    
Probe: MGI:6363247
Assay Type: Western blot
Annotation Date: 2019-10-11
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:6363357
Age: postnatal adult
Image: 4
Specimen Label: Control
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6363247
Assay Type: Western blot
Annotation Date: 2019-10-11
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:6363357
Age: postnatal adult
Image: 4
Specimen Label: Control
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6363247
Assay Type: Western blot
Annotation Date: 2019-10-11
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:6363357
Age: postnatal adult
Image: 4
Specimen Label: Rgs2 KO
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6363247
Assay Type: Western blot
Annotation Date: 2019-10-11
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:6363357
Age: postnatal adult
Image: 4
Specimen Label: Rgs2 KO
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6468327
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160352
Pattern: Not Specified
Stage: TS02
Assay Id: MGI:6468578
Age: embryonic day 1.0
Image: 5B Control
Specimen Label: 5B Control
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6468327
Assay Type: Immunohistochemistry
Annotation Date: 2020-10-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160352
Pattern: Not Specified
Stage: TS02
Assay Id: MGI:6468578
Age: embryonic day 1.0
Image: 5B cKO
Note: The zona pellucida is defective in the mutant.
Specimen Label: 5B cKO
Detected: true
Specimen Num: 2
Publication
First Author: O'Toole CM
Year: 2000
Journal: Mol Biol Cell
Title: Ca(2+) entry through store-operated channels in mouse sperm is initiated by egg ZP3 and drives the acrosome reaction.
Volume: 11
Issue: 5
Pages: 1571-84
Publication
First Author: El-Mestrah M
Year: 2002
Journal: Biol Reprod
Title: Subcellular distribution of ZP1, ZP2, and ZP3 glycoproteins during folliculogenesis and demonstration of their topographical disposition within the zona matrix of mouse ovarian oocytes.
Volume: 66
Issue: 4
Pages: 866-76
Publication
First Author: Harris JD
Year: 1994
Journal: DNA Seq
Title: Cloning and characterization of zona pellucida genes and cDNAs from a variety of mammalian species: the ZPA, ZPB and ZPC gene families.
Volume: 4
Issue: 6
Pages: 361-93
Publication
First Author: Rankin T
Year: 1996
Journal: Mol Hum Reprod
Title: The molecular genetics of the zona pellucida: mouse mutations and infertility.
Volume: 2
Issue: 11
Pages: 889-94
Publication
First Author: Bernhardt ML
Year: 2015
Journal: Development
Title: Regulator of G-protein signaling 2 (RGS2) suppresses premature calcium release in mouse eggs.
Volume: 142
Issue: 15
Pages: 2633-40
Publication
First Author: Xu H
Year: 2012
Journal: Reproduction
Title: Sperm arylsulfatase A binds to mZP2 and mZP3 glycoproteins in a nonenzymatic manner.
Volume: 144
Issue: 2
Pages: 209-19
Publication
First Author: Malek SN
Year: 1996
Journal: J Biol Chem
Title: p150TSP, a conserved nuclear phosphoprotein that contains multiple tetratricopeptide repeats and binds specifically to SH2 domains.
Volume: 271
Issue: 12
Pages: 6952-62
Publication
First Author: Xu W
Year: 1995
Journal: Genomics
Title: Uroporphyrinogen-III synthase: molecular cloning, nucleotide sequence, expression of a mouse full-length cDNA, and its localization on mouse chromosome 7.
Volume: 26
Issue: 3
Pages: 556-62
Publication
First Author: Lyon MF
Year: 1990
Journal: Proc Natl Acad Sci U S A
Title: The scurfy mouse mutant has previously unrecognized hematological abnormalities and resembles Wiskott-Aldrich syndrome.
Volume: 87
Issue: 7
Pages: 2433-7