| Primary Identifier | MGI:2178928 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Itk |
| Transmission | Germline | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| description | J1 and CCE were used in the generation of this targeted mutation. |
| molecularNote | The kinase domain of this gene (amino acids 476-543) spanning from the middle of exon 10 to exon 12 was replaced with a PGK-neo cassette via homologous recombination. Protein product was absent in lymph nodes, spleen, and thymus of homozygous mutant animals via Western blot analysis. |
