Primary Identifier | MGI:5636485 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Th-ALK*F1174L)2Loch |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The human ALK cDNA with the F1174L mutation is under the control of the rat tyrosine hydroxylase promoter, which drives expression in committed sympathetic precursor cells of the neural crest. Four lines were established; 1, 2, 3, and 4. Line 2 is entered as a representative line. |