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Protein Coding Gene : Retsat retinol saturase (all trans retinol 13,14 reductase)

Primary Identifier  MGI:1914692 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  67442
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables all-trans-retinol 13,14-reductase activity. Involved in retinol metabolic process. Located in endoplasmic reticulum membrane and nuclear outer membrane. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; hemolymphoid system gland; and nervous system. Orthologous to human RETSAT (retinol saturase).
PHENOTYPE: Mice homozygous for a knock-out allele are deficient in the production of all-trans-13,14-dihydroretinol from dietary vitamin A and exhibit increased adiposity. [provided by MGI curators]
  • synonyms:
  • Retsat,
  • MGI:2141759,
  • RIKEN cDNA 0610039N19 gene,
  • retinol saturase (all trans retinol 13,14 reductase),
  • expressed sequence C80029,
  • C80029,
  • 0610039N19Rik

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1 Involved In Mutations

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

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