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Protein Coding Gene : Wdfy4 WD repeat and FYVE domain containing 4

Primary Identifier  MGI:3584510 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  545030
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Acts upstream of or within with a positive effect on CD8-positive, alpha-beta T cell activation. Acts upstream of or within antigen processing and presentation and cellular response to virus. Predicted to be located in endoplasmic reticulum and endosome. Orthologous to human WDFY4 (WDFY family member 4).
PHENOTYPE: Mice homozygous for a null allele exhibit reduced CD103+ CD11bneg migratory cDC1 cells in the mesenteric lymph nodes and failure to reject 1969 sarcoma cells. [provided by MGI curators]
  • synonyms:
  • Wdfy4,
  • WD repeat and FYVE domain containing 4

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For