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Protein Coding Gene : Lpp LIM domain containing preferred translocation partner in lipoma

Primary Identifier  MGI:2441849 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  210126
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable metal ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to act upstream of or within cell adhesion. Predicted to be located in cytosol. Predicted to be active in focal adhesion and stress fiber. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system; and musculoskeletal system. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human LPP (LIM domain containing preferred translocation partner in lipoma).
PHENOTYPE: Gene disruption results in fertility problems involving females but not males. Migration and survival of MEFs are also abnormal. [provided by MGI curators]
  • synonyms:
  • expressed sequence AA959454,
  • RIKEN cDNA B130055L10 gene,
  • RIKEN cDNA 9430020K16 gene,
  • AA959454,
  • expressed sequence C79715,
  • AU024130,
  • expressed sequence AU024130,
  • B130055L10Rik,
  • MGI:2146367,
  • MGI:2146704,
  • 9430020K16Rik,
  • Lpp,
  • MGI:2146570,
  • C79715,
  • LIM domain containing preferred translocation partner in lipoma

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