Primary Identifier | MGI:2685369 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 245827 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to enable calcium ion binding activity. Predicted to be involved in cell-substrate adhesion; epithelial cell migration; and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in Golgi apparatus; anchoring junction; and plasma membrane. Predicted to be active in adherens junction. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; nose; and urinary system. Human ortholog(s) of this gene implicated in spinocerebellar ataxia 45. Orthologous to human FAT2 (FAT atypical cadherin 2). PHENOTYPE: Mice homozygous for a knock-out allele are healthy, fertile and overtly normal, with no apparent defects in the development of red blood cells or platelets. [provided by MGI curators] |