| Primary Identifier | MGI:5473821 | Allele Type | Transgenic |
| Attribute String | Conditional ready, Dominant negative, Inserted expressed sequence, Reporter | Gene | Tg(CAG-Bmpr1a*,-lacZ)1Nobs |
| Strain of Origin | C57BL/6J x B6;129X1-Pcp2<tm1(cre)Nobs> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | This transgene consists of the CAG promoter, loxP flanked stop codon, a 0.6 kb dominant-negative mouse Bmpr1a cDNA lacking the intracellular kinase domain (Y176STOP), a 0.5 kb internal ribosomal entry site (IRES), a 3.5 kb lacZ gene containing the nuclear localization signal, and a polyadenylation signal. Upon Cre-mediated excision of the Stop codon, the modified allele expresses the dominant negative Bmpr1a and lacZ in tissues where Cre is expressed. |
