|  Help  |  About  |  Contact Us

Protein Coding Gene : Kcnb2 potassium voltage gated channel, Shab-related subfamily, member 2

Primary Identifier  MGI:99632 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  98741
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable delayed rectifier potassium channel activity; protein heterodimerization activity; and transmembrane transporter binding activity. Predicted to be involved in potassium ion transmembrane transport and protein localization to plasma membrane. Predicted to act upstream of or within monoatomic ion transmembrane transport. Predicted to be located in neuronal cell body membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in dendrite and neuronal cell body. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system gland; liver; and sensory organ. Orthologous to human KCNB2 (potassium voltage-gated channel subfamily B member 2).
PHENOTYPE: Mice homozygous for a targeted mutation exhibit neurological abnormalities when compared with controls, including an abnormal sleep/wake cycle, decreased exploratory and locomotor activity, and a motor strength deficit. [provided by MGI curators]
  • synonyms:
  • Kcnb2,
  • 9630047L19Rik,
  • expressed sequence BB130875,
  • RIKEN cDNA 9630047L19 gene,
  • Kv2.2,
  • MGD-MRK-16417,
  • potassium voltage gated channel, Shab-related subfamily, member 2,
  • BB130875,
  • MGI:2138636

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For