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Allele : Mstn<em2(Gdf11)Rlee> myostatin; endonuclease-mediated mutation 2, Richard T Lee
Primary Identifier  MGI:7568819 Allele Type  Endonuclease-mediated
Gene  Mstn Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  The sequence coding for the mature domain (aspartic acid codon 268 through serine codon 376) in exon 3 was replaced with the equivalent sequence from paralog Gdf11 (asparagine codon 297 through serine codon 405) using sgRNAs and a dsODN template with CRISPR/Cas9 technology.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Gdf8<11MD>,
  • Gdf8<Gdf11MD>,
  • Gdf8<11MD>,
  • Gdf8<Gdf11MD>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories





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