| Primary Identifier | MGI:5425899 | Allele Type | Targeted |
| Attribute String | Modified isoform(s) | Gene | Col2a1 |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 2 was replaced with an exon 2 in which nucleotide substitutions (ACT GCC AGT Ggtcgta to ACG GCC AGT Ggtaagt) resulted in a silent mutation to produce an HaeIII site and mutate the exon IIa 5' splice site. Cre-mediated recombination removed a floxed neo cassette inserted downstream of the modified exon 2. Mice only express isoform IIa. |
