Primary Identifier | MGI:2673064 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 240873 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Enables identical protein binding activity and tumor necrosis factor receptor superfamily binding activity. Involved in several processes, including regulation of T cell activation; regulation of leukocyte chemotaxis; and tumor necrosis factor-mediated signaling pathway. Located in cell surface. Is expressed in skin; submandibular gland; and thyroid gland. Orthologous to human TNFSF18 (TNF superfamily member 18). PHENOTYPE: Liver progenitor cell-specific conditional knock-out mice show attenuated ductular reaction, liver inflammation and liver fibrosis upon liver injury induced by feeding a choline-deficient diet supplemented with ethionine. [provided by MGI curators] |