Primary Identifier | MGI:1919086 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 71836 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in positive regulation of chromosome organization and spermatogenesis. Located in meiotic spindle. Orthologous to human SHCBP1L (SHC binding and spindle associated 1 like). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced male fertility with reduced sperm, increased male germ cell apoptosis and spindle instability. [provided by MGI curators] |