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Protein Domain : F-box only protein 31

Primary Identifier  IPR026941 Type  Family
Short Name  FBXO31
description  F-box only protein 31 is a component of the SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. It specifically recognises phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest [, ].

0 Child Features

1 Parent Features

2 Protein Domain Regions