Primary Identifier | MGI:1913370 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 66120 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in chaperone-mediated protein folding. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including craniocervical region bone; incisor; liver lobe; pancreas tip epithelium; and thoracic segment skeleton. Orthologous to human FKBP11 (FKBP prolyl isomerase 11). PHENOTYPE: Mice homozygous for disruptions of this gene display increased antibody response to antibody challenge and increased inflammatory responses. Measurements of bone density are also increased. [provided by MGI curators] |