Primary Identifier | MGI:5613976 | Allele Type | Transgenic |
Attribute String | Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter | Gene | Tg(EEF1A1-SHC1)1Ravi |
Strain of Origin | 129S | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgenic construct contains a human eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) promoter/enhancer elements driving expression of a wildtype flag-tagged human src homology 2 domain-containing transforming protein C1 (SHC1) cDNA. The SHC1 sequence is fused to an internal ribosome entry site (IRES)-enhanced green fluorescent protein (EGFP) fusion protein, and is preceded by a loxP-flanked SV40 polyadenylation signal. |