Primary Identifier | IPR043037 | Type | Homologous_superfamily |
Short Name | CfaE_adhesin |
description | CfaE, the tip adhesin of enterotoxigenic Escherichia coli colonisation factor antigen I fimbriae (CFA/I), initiates binding of this enteropathogen to the small intestine. It comprises a stacked N-terminal β-sandwich adhesin domain (AD) and a C-terminal pilin domain (PD), with the putative receptor-binding pocket at one pole and an equatorial interdomain interface [, ].This superfamily represents the adhesin domain of CfaE, homologous to the pilus biogenesis initiator protein CbID and the major pilin subunits of CS pili. |