Primary Identifier | MGI:5692468 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Cd177 |
Transmission | Germline | Strain of Origin | C57BL/6N-A<tm1Brd> |
Is Recombinase | false | Is Wild Type | false |
Project Collection | KOMP-CSD |
molecularNote | The insertion of the L1L2_Bact_P cassette created a deletion of size 5769 starting at position 24453503 and ending at position 24459272 of Chromosome 7 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml |