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Gene Segment : Igh-8 immunoglobulin heavy chain 8 (heavy chain of IgG3)
Primary Identifier  MGI:96450 Organism  mouse, laboratory
Chromosome  12 Mgi Type  gene segment
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables antigen binding activity. Acts upstream of or within phagocytosis; positive regulation of immune response; and positive regulation of phagocytosis. Part of immunoglobulin complex, circulating. Is expressed in several structures, including exocrine gland; hemolymphoid system gland; intestine; limb segment; and liver and biliary system.
PHENOTYPE: Mice homozygous for disruptions in this gene display poor T-cell independent immune responses. [provided by MGI curators]
  • synonyms:
  • Igh-8,
  • immunoglobulin heavy chain 8 (heavy chain of IgG3),
  • MGD-MRK-11247
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