| First Author | Birchmeier W | Year | 1995 |
| Journal | Bioessays | Volume | 17 |
| Issue | 2 | Pages | 97-9 |
| PubMed ID | 7748170 | Mgi Jnum | J:23333 |
| Mgi Id | MGI:71092 | Doi | 10.1002/bies.950170203 |
| Citation | Birchmeier W (1995) E-cadherin as a tumor (invasion) suppressor gene. Bioessays 17(2):97-9 |
| abstractText | Diffuse-type gastric carcinomas show diminished cell-cell adhesion. A recent paper reports that 50% of these carcinomas contain mutations in the E-cadherin gene, resulting in the destruction of the calcium-binding sites of E-cadherin, and providing strong in vivo evidence that alterations in E-cadherin play a major role in the development of this particular type of cancer and the short survival of the patients. |
