| First Author | Hogarth PM | Year | 1987 |
| Journal | Immunogenetics | Volume | 26 |
| Issue | 3 | Pages | 161-8 |
| PubMed ID | 2957319 | Mgi Jnum | J:37832 |
| Mgi Id | MGI:85228 | Doi | 10.1007/BF00365906 |
| Citation | Hogarth PM, et al. (1987) The mouse Fc receptor for IgG (Ly-17): molecular cloning and specificity. Immunogenetics 26(3):161-8 |
| abstractText | A cDNA clone encoding the mouse Ly-17+ Fc receptor for IgG, isolated from a myelomonocytic cell line, was sequenced and expression of mRNA and the functional Fc gamma R investigated. The receptor is a 301 amino acid transmembrane glycoprotein with two homologous extracellular domains that are also homologous to members of the Ig superfamily. The receptor has four sites of N-linked glycosylation and a long 94 amino acid cytoplasmic tail. Northern analysis, immune complex binding, and serological studies demonstrate that the receptor encoded by the cDNA clone binds mouse IgG gamma 1/2b and rabbit IgG complexes. |
