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Protein Domain : Calcium uptake protein 1/2/3

Primary Identifier  IPR039800 Type  Family
Short Name  MICU1/2/3
description  This entry represents a group of calcium uptake proteins, including MICU1/2/3 from humans. They contain the conserved EF-hand Ca2+-binding domains. MICU1 and MICU2 are the main regulators of the mitochondrial Ca(2+)-uniporter (MCU) []. MICU2 forms a heterodimer with MICU1 to modulate MCU channel activity []. MICU3 a tissue-specific enhancer of mitochondrial calcium uptake [].

0 Child Features

0 Parent Features

9 Protein Domain Regions