First Author | Jomary C | Year | 1995 |
Journal | Brain Res Mol Brain Res | Volume | 29 |
Issue | 1 | Pages | 172-6 |
PubMed ID | 7769994 | Mgi Jnum | J:23289 |
Mgi Id | MGI:71054 | Doi | 10.1016/0169-328x(94)00252-a |
Citation | Jomary C, et al. (1995) Spatio-temporal pattern of ocular clusterin mRNA expression in the rd mouse. Brain Res Mol Brain Res 29(1):172-6 |
abstractText | To define the relationship between progressive photoreceptor degeneration and clusterin upregulation, we analysed the spatio-temporal distribution and level of clusterin mRNA in the retinal degeneration (rd) mouse. Expression was increased in the retinal pigment epithelium and inner retina, but not detected in the photoreceptors. These results indicate that increased clusterin mRNA is not causally involved in apoptotic mechanisms of photoreceptor death but may relate to lipid-recycling or cytoprotective functions. |