Primary Identifier | MGI:95757 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 20527 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables D-glucose transmembrane transporter activity and dehydroascorbic acid transmembrane transporter activity. Involved in dehydroascorbic acid transport and glucose transmembrane transport. Located in acrosomal membrane and plasma membrane. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; early conceptus; and genitourinary system. Orthologous to several human genes including SLC2A3 (solute carrier family 2 member 3). PHENOTYPE: Homozygous null mutations cause embryonic lethality. Heterozygotes for a null allele show partial perinatal lethality and impaired placental transport. Heterozygotes for a gene trap allele show abnormal brain wave patterns, increased startle reflex, reduced prepulse inhibition and increased anxiety. [provided by MGI curators] |