| First Author | Mitelman F | Year | 1986 |
| Journal | Cancer Genet Cytogenet | Volume | 22 |
| Issue | 2 | Pages | 95-8 |
| PubMed ID | 3458521 | Mgi Jnum | J:24094 |
| Mgi Id | MGI:72852 | Doi | 10.1016/0165-4608(86)90168-8 |
| Citation | Mitelman F, et al. (1986) High resolution chromosome analysis of constitutional and acquired t(15;17) maps c-erbA to subband 17q11.2. Cancer Genet Cytogenet 22(2):95-8 |
| abstractText | High resolution chromosome analysis was performed on bone marrow cells from four patients with acute promyelocytic leukemia and t(15;17), and in lymphocytes from two unrelated, phenotypically normal persons with an apparently identical constitutional translocation. Scrutiny of prophase-prometaphase chromosomes localized the breakpoints in all six cases to subbands 15q22.3 and 17q11.2. Molecular genetic studies have localized the oncogene c-erbA to chromosome #17 between the breakpoints of the constitutional and the acquired anomaly. The present results, therefore, map c-erbA to subband 17q11.2. |
