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Allele : Gata1<tm2.1Yen> GATA binding protein 1; targeted mutation 2.1, Hsin-Fang Yang-Yen
Primary Identifier  MGI:5521598 Allele Type  Targeted
Gene  Gata1 Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 2 was replaced with a modified exon 2 in which nucleotide substitutions (TCA to GCC) results in the amino acid susbtitution of alanine for serine at position 26 (S26A). This mutation prevents phosphorylation at this site. Cre-mediated recombination removed the floxed neomycin resistance cassette inserted downstream of the modified exon 2.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • GATA-1<S26A>,
  • GATA-1<S26A>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

4 Publication categories

Trail: Allele




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