Primary Identifier | MGI:2387093 | Allele Type | Targeted |
Attribute String | Not Specified | Gene | Cebpa |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A partial rat Cebpa gene carring an isoleucine to alanine substitution at position 294 (I294A) and an arginine to alanine substitution at position 297 (R297A) in the basic region alpha helix replaced the corresponding portion of the mouse gene via homologous recombination. A neo resistance marker was also introduced downstream of Cepba for positive selection. |