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Protein Coding Gene : Slk STE20-like kinase

Primary Identifier  MGI:103241 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  20874
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable histone kinase activity; protein homodimerization activity; and protein serine/threonine kinase activity. Involved in regulation of cell migration. Located in cell leading edge. Is expressed in several structures, including alimentary system; genitourinary system; musculature; nervous system; and sensory organ. Orthologous to human SLK (STE20 like kinase).
PHENOTYPE: Mice homozygous for a gene trapped allele die by E14.5, exhibiting severe developmental defects, impaired neuronal and skeletal muscle development, abnormal placental differentiation and vascularization, and increased apoptosis. [provided by MGI curators]
  • synonyms:
  • expressed sequence AW411554,
  • MGD-MRK-24116,
  • MGI:2147668,
  • expressed sequence AV021402,
  • mKIAA0204,
  • SLK,
  • Slk,
  • serine/threonine kinase 2,
  • AV021402,
  • 9A2,
  • STE20-like kinase,
  • Etk4,
  • AW411554,
  • Stk2,
  • MGI:2147725,
  • mSLK

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

2 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For