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Publication : Structure and chromosome location of Smtn, the mouse smoothelin gene.

First Author  Rensen S Year  2000
Journal  Cytogenet Cell Genet Volume  89
Issue  3-4 Pages  225-9
PubMed ID  10965129 Mgi Jnum  J:64406
Mgi Id  MGI:1889183 Doi  10.1159/000015619
Citation  Rensen S, et al. (2000) Structure and chromosome location of Smtn, the mouse smoothelin gene. Cytogenet Cell Genet 89(3-4):225-9
abstractText  Smoothelins are cytoskeleton-associated proteins that are found in contractile smooth muscle. Two isoforms have been identified: smoothelin-A, expressed in visceral tissues and smoothelin-B, found in vascular tissues. The mouse smoothelin gene (Smtn) was isolated and characterized. It was assigned to chromosome 11 band A2-A3 by fluorescence in situ hybridization. The gene consists of 20 exons and spans 23 kb. Its structure is conserved between mouse and human. The proximal promoter of both smoothelin-A and smoothelin-B contains several transcription factor-binding sites but lacks a consensus TATA box. Copyright 2000 S. Karger AG, Basel.
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