Primary Identifier | IPR027757 | Type | Family |
Short Name | REST |
description | The Repressor Element-1 (RE-1) Silencing Transcription (REST) factor is a transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells [, ]. REST is involved in neural differentiation and in preservation of the neural phenotype. REST also plays a role in proliferation, although its effect differs depending on the cell type []. |