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Comment :

Type  MGI:General Description  homozygotes were viable, resistant to collagenase action, and developed normally to young adulthood at ~7 months, homozygotes developed dermal fibrosis, similar to scleroderma, and skin ulcerations mutant skin displayed a significant increase in collagen extending through to the deep dermis homozygous females developed similar but milder skin abnormalities relative to age-matched homozygous males