Type | MGI:General | Description | homozygotes were viable, resistant to collagenase action, and developed normally to young adulthood at ~7 months, homozygotes developed dermal fibrosis, similar to scleroderma, and skin ulcerations mutant skin displayed a significant increase in collagen extending through to the deep dermis homozygous females developed similar but milder skin abnormalities relative to age-matched homozygous males |