Type | MGI:General | Description | in contrast to wild-type, homozygotes showed resistance to PTH-induced bone resorption, with only a few resorption spaces and rare osteoclasts the bone resorption area and the number of osteoclasts/mm2 were significantly increased (~5-fold) after PTH injection in wild-type, but not in homozygous mutant mice homozygotes were not resistant to other skeletal effects of PTH after i.p. injection of PTH, calcemic responses were significantly lower in homozygotes versus wild-type |