| Primary Identifier | MGI:3767571 | Allele Type | Chemically induced (ENU) |
| Gene | Tlr9 | Inheritance Mode | Other (see notes) |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false | Project Collection | Beutler Mutagenetix |
| description | The inheritance of the phenotype associated with this mutation is likely semidominant, as are other mutations at this locus, but heterozygous mutant mice have not been characterized. (J:128406) |
| molecularNote | The Cpg3 phenotype was identified in an ENU mutagenesis screen for mutants with impaired response to Toll-like receptor (TLR) ligands. The mutation is a T-to-A transversion at nucleotide position 747 of the gene (Genbank Accession NM_031178) that results in replacement of valine by glutamic acid at amino acid position 214 of the receptor protein. |
