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Allele : Fgf10<Tg(Myl3-lacZ)24Buck> fibroblast growth factor 10; transgene insertion 24, Margaret E Buckingham

Primary Identifier  MGI:3629660 Allele Type  Transgenic
Attribute String  Hypomorph, Reporter Gene  Fgf10
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene contains 757 bp upstream of the transcriptional start site, the 5' UTR and the first 33 codons of the mouse myosin light polypeptide 3 gene upstream of nlacZ. The promoter contains a 34 bp deletion at -150 relative to the transcription start site. Two to three copies of the transgene integrated 114 kb upstream of the locus in a head-to-tail array. Expression of the transgene is in a highly similar pattern to that of Fgf10 in the embryo. Whole mount in-situ analysis detected decreased expression of the endogenous gene in homozygous embryos indicating this is a hypomorphic allele.
  • mutations:
  • Insertion
  • synonyms:
  • Fgf10<lacZ>,
  • Fgf10<Mlc1v-nLacZ-v24>,
  • Fgf10<Mlcv-nlacZ-v24>,
  • Mlc1v-nlacZ-24,
  • Fgf10<->,
  • Fgf10<mlcv>,
  • Fgf10<lacZ>,
  • Fgf10<->,
  • Mlc1v-nlacZ-24,
  • Fgf10<mlcv>,
  • Fgf10<Mlc1v-nLacZ-v24>,
  • Fgf10<Mlcv-nlacZ-v24>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

47 Publication categories

Trail: Allele