Primary Identifier | MGI:3624441 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Rb1 |
Transmission | Germline | Strain of Origin | 129T2/SvEms |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin resistance cassette flanked by FRT sites and with a 5' loxP site was inserted in intron 1. An additional loxP site was also inserted in intron 2. The neomycin cassette was subsequently excised by crossing with flpe-deleter mice. Exon 2 was then removed by crossing with Tg(CMV-cre)1Cgn mice. |