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Allele : Guca1a/Guca1b<tm1Jnc> guanylate cyclase activator 1a (retina); targeted mutation 1, Jeannie Chen
Primary Identifier  MGI:2664159 Allele Type  Targeted
Attribute String  Null/knockout Gene  Guca1a
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Guca1a and Guca1b, which are arranged tail-to-tail, were disrupted by the insertion of a single neo cassette. The deleted region encompassed exons 2 through 4 of Guca1a and exons 3 and 4 of Guca1b. Immunostaining and Western blot analysis of homozygous mutant retinal tissue indicated an absence of proteins.
  • mutations:
  • Intergenic deletion,
  • Insertion
  • synonyms:
  • GCAPs<->,
  • GCAPs<->,
  • GCAP<->,
  • GCAP<->,
  • GCAP1<->GCAP2<->,
  • GCAP1<->GCAP2<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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