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Publication : Strong teratocarcinoma transplantation loci, Gt-1 and Gt-2, flank H-2.

First Author  Shedlovsky A Year  1981
Journal  Immunogenetics Volume  13
Issue  5 Pages  413-9
PubMed ID  7298086 Mgi Jnum  J:6632
Mgi Id  MGI:55107 Doi  10.1007/BF00346022
Citation  Shedlovsky A, et al. (1981) Strong teratocarcinoma transplantation loci, Gt-1 and Gt-2, flank H-2. Immunogenetics 13(5):413-9
abstractText  Evidence is presented for the existence of two strong murine teratocarcinoma transplantation antigens (Gt) on the cell line PCC3. It is shown that the loci governing expression of these antigens are linked to the H-2 complex. These loci have been further mapped with respect to the brachyury marker (T) and H-2: Gt-1 lies 5 +/- 2 crossover units proximal to H-2 and 12 +/- 2 crossover units distal to T; Gt-2 lies 21 +/- 4 crossover units distal to H-2. It is possible that these strong transplantation antigens provide an embryonic analogue to the adult major histocompatibility system.
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