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Allele : Pdgfc<tm3633Arte> platelet-derived growth factor, C polypeptide; targeted mutation 3633, TaconicArtemis

Primary Identifier  MGI:6194942 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Pdgfc
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
molecularNote  Based on NCBI transcript NM_019971_2, nucleotide substitutions were made that altered the following codons: K242T, K246R and R299S mutations have been introduced into exon 5, and K318R, N342S and A343T mutations have been introduced into exon 6. These mutations alter the mouse sequences to mimic the human amino acid sequence.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Pdgfc<tm3633(K242T, K246R, R299S, K318R, N342S, A343T)Arte>,
  • PDGF-CC<hum>,
  • Pdgfc<tm3633(K242T, K246R, R299S, K318R, N342S, A343T)Arte>,
  • PDGF-CC<hum>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele