| First Author | Kotani T | Year | 1993 |
| Journal | Gene | Volume | 123 |
| Issue | 2 | Pages | 289-90 |
| PubMed ID | 7916704 | Mgi Jnum | J:3942 |
| Mgi Id | MGI:52447 | Doi | 10.1016/0378-1119(93)90141-o |
| Citation | Kotani T, et al. (1993) Nucleotide sequence of the cDNA encoding mouse thyroid peroxidase. Gene 123(2):289-90 |
| abstractText | The nucleotide (nt) sequence of the cDNA encoding mouse thyroid peroxidase (TPO) has been determined. The TPO cDNA is 3281 nt long and its open reading frame encodes a protein composed of 914 amino acids (aa), including a putative initiation Met. The mouse TPO cDNA shows 75.3, 70.8, and 93.5% homology in the coding nt sequence with human, porcine, and rat TPO cDNAs, respectively. In the aa sequence, mouse TPO shows 73.4, 68.4, and 93.9% homology with human, porcine, and rat TPOs, respectively. Specifically, the aa sequence surrounding the proximal His residue, probably essential for TPO activity, is well conserved among these four organisms. |
