| Primary Identifier | IPR003027 | Type | Family |
| Short Name | Rec1_exonuc_Ustilaginaceae |
| description | Rec1 of Ustilago maydis is a homologue of S. pombe Rad1 and S. cerevisiae Rad17 proteins. It plays a key role in regulating the genetic systemof the fungus. Rec1 mutants are very sensitive to UV light - mutationleads to a complex phenotype with alterations in DNA repair, recombination,mutagenesis, meiosis and cell division. The predicted product of theREC1 gene is a polypeptide of 522 amino acid residues with molecular mass 57 kD. The protein shows 3'--5' exonuclease activity, but only in cellsover-expressing Rec1. While it is distinguishable from the majorbacterial nucleases, the protein has certain enzymatic features in commonwith epsilon, the proof-reading exonuclease subunit of Escherichia coli DNA polymeraseIII holoenzyme []. |
