Primary Identifier | MGI:6192700 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(KRT14-COL5A1)#Flru |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene comprises the following elements: the human keratin 14 promoter up to the translation start site, human collagen type V alpha 1 cDNA, and KRT14 3' UTR sequence including poly(A) signal. The construct was microinjected into male pronuclei of fertilized oocytes. Immunoblots and RT-PCR confirmed this transgene drives the expression of COL5A1 in the epidermis. |