| First Author | Mezquita J | Year | 1998 |
| Journal | Mol Reprod Dev | Volume | 50 |
| Issue | 1 | Pages | 70-8 |
| PubMed ID | 9547512 | Mgi Jnum | J:46517 |
| Mgi Id | MGI:1201266 | Doi | 10.1002/(SICI)1098-2795(199805)50:1<70::AID-MRD9>3.0.CO;2-U |
| Citation | Mezquita J, et al. (1998) Four isoforms of the signal-transduction and RNA-binding protein QKI expressed during chicken spermatogenesis. Mol Reprod Dev 50(1):70-8 |
| abstractText | Genes expressed during spermatogenesis undergo alternative initiation and alternative splicing and may be under the control of a coordinated mechanism of RNA processing. A family of proteins that combine features of signal-transduction and RNA-binding molecules could be instrumental in this process. We have characterized a cDNA from adult chicken testis that codifies a highly conserved orthologue of the mouse quaking gene qki. The predicted chicken protein differs only in four amino acids from the corresponding mouse protein. Messages of 7, 6, and 5 kb are expressed differentially during chicken spermatogenesis. The 5-kb message, the predominant form in adult testis, presents heterogeneity in the coding region, showing insertions of 51 and 75 bp and a deletion of 24 bp, which gives rise to four possible isoforms of the protein. |
